[HTML][HTML] Recent advances in leishmaniasis treatment

TS Tiuman, AO Santos, T Ueda-Nakamura… - International Journal of …, 2011 - Elsevier
About 1.5 million new cases of cutaneous leishmaniasis and 500 000 new cases of visceral
leishmaniasis occur each year around the world. For over half a century, the clinical forms of …

Chemistry and Biological Activities of Terpenoids from Copaiba (Copaifera spp.) Oleoresins

LM Leandro, F de Sousa Vargas, PCS Barbosa… - Molecules, 2012 - mdpi.com
Copaiba oleoresins are exuded from the trunks of trees of the Copaifera species
(Leguminosae-Caesalpinoideae). This oleoresin is a solution of diterpenoids, especially …

Copaifera of the Neotropics: A Review of the Phytochemistry and Pharmacology

R Da Trindade, JK Da Silva, WN Setzer - International Journal of …, 2018 - mdpi.com
The oleoresin of Copaifera trees has been widely used as a traditional medicine in
Neotropical regions for thousands of years and remains a popular treatment for a variety of …

[HTML][HTML] Syzygium cumini (L.) Skeels essential oil and its major constituent α-pinene exhibit anti-Leishmania activity through immunomodulation in vitro

KA da Franca Rodrigues, LV Amorim, CN Dias… - Journal of …, 2015 - Elsevier
Ethnopharmacological relevance Syzygium cumini (L.) Skeels (Myrtaceae), commonly
known as “jambolão” in Brazil is widely used in folk medicine against leishmaniasis …

[HTML][HTML] Occurrence, chemical composition, biological activities and analytical methods on Copaifera genus—A review

C Arruda, JAA Mejía, VP Ribeiro, CHG Borges… - Biomedicine & …, 2019 - Elsevier
Copaifera is a genus of large trees found in Brazil, mainly in Amazon forest, but also in
Atlantic forest and cerrado biomes. It has also been found in other countries in South …

Terpenes from Copaifera Demonstrated in Vitro Antiparasitic and Synergic Activity

E Izumi, T Ueda-Nakamura, VF Veiga Jr… - Journal of Medicinal …, 2012 - ACS Publications
To discover new possible therapies for Chagas' disease, we evaluated against all
Trypanosoma cruzi life stages the in vitro trypanocidal and synergistic activity of terpenes …

Essential oils: in vitro activity against Leishmania amazonensis, cytotoxicity and chemical composition

MA Andrade, CS Azevedo, FN Motta, ML Santos… - … and alternative medicine, 2016 - Springer
Background The current chemotherapy for cutaneous leishmaniosis (CL) has a series of
drug limitations such as toxic side effects, long duration, high costs and drug resistance …

GC–MS profiling of the phytochemical constituents of the oleoresin from Copaifera langsdorffii Desf. and a preliminary in vivo evaluation of its antipsoriatic effect

F Gelmini, G Beretta, C Anselmi, M Centini… - International journal of …, 2013 - Elsevier
Copaiba is the oleoresin (OR) obtained from Copaifera (Fabaceae), a neotropical tree which
grows in Amazon regions. The balsam, constituted by an essential oil and a resinous …

Antileishmanial and cytotoxic potential of essential oils from medicinal plants in Northern Tunisia

R Essid, FZ Rahali, K Msaada, I Sghair… - Industrial Crops and …, 2015 - Elsevier
The current study investigated the putative antileishmanial and cytotoxic activity of twelve
essential oils (EOs) and their major components on Leishmania (L.) major and Leishmania …

Eugenia uniflora L. Essential Oil as a Potential Anti‐Leishmania Agent: Effects on Leishmania amazonensis and Possible Mechanisms of Action

KAF Rodrigues, LV Amorim… - Evidence‐Based …, 2013 - Wiley Online Library
Eugenia uniflora L. is a member of the Myrtaceae family and is commonly known as
Brazilian cherry tree. In this study, we evaluated the chemical composition of Eugenia …