Senescent cells (SCs) arise from normal cells in multiple organs due to inflammatory,
metabolic, DNA damage, or tissue damage signals. SCs are non-proliferating but …

The acute respiratory distress syndrome (ARDS) is a life-threatening lung condition resulting
from direct and indirect insults to the lung. It is characterized by disruption of the endothelial …

Acute lung injury (ALI) is due to an uncontrolled systemic inflammatory response resulting
from direct injury to the lung or indirect injury in the setting of a systemic process. Such …

Immune cells of the monocyte/macrophage lineage are characterized by their diversity,
plasticity, and variety of functions. Among them, macrophages play a central role in antiviral …

We have previously shown that the prophylactic treatment with cannabidiol (CBD) reduces
inflammation in a model of acute lung injury (ALI). In this work we analyzed the effects of the …

Background Resveratrol (RSV) has attracted interest as an alternative drug for the treatment
of acute lung injury (ALI) and other pulmonary diseases, but its poor oral bioavailability is a …

Bacterial flagellin is critical to mediate NLRC4 inflammasome-dependent caspase-1
activation. However, Shigella flexneri, a nonflagellated bacterium, and a flagellin (fliC) …

The term primary graft dysfunction (PGD) incorporates a continuum of disease severity from
moderate to severe acute lung injury (ALI) within 72 h of lung transplantation. It represents …

PAR1 plays a central role in mediating the interplay between coagulation and inflammation,
but its role in regulating acute neutrophilic inflammation is unknown. We report that …

Transfusion-related acute lung injury (TRALI) is one of the leading causes of transfusion-
related fatalities and is characterized by the onset of acute respiratory distress within 6 hours …