The prevalence of alcohol use disorder (AUD) has been steadily increasing over the past
decade. In parallel, alcohol-associated liver disease (ALD) has been increasing at an …

Heavy drinking and alcohol use disorder are major public health problems. Practitioners not
specialising in alcohol treatment are often unaware of the guidelines for preventing …

The goal of this guideline1 is to improve the quality of care and treatment outcomes for
patients with alcohol use disorder (AUD), as defined by DSM-5 (American Psychiatric …

Macronutrients and trace elements are important components of living tissues that have
different metabolic properties and functions. Trace elements participate in the regulation of …

The interplay between excitatory and inhibitory circuits underlies the brain's processes and
their dysregulation has been linked to cognitive decline, psychiatric disorders and epilepsy …

Pathologic alcohol use affects more than 2 billion people and accounts for nearly 6% of all
deaths worldwide. There are three medications approved for the treatment of alcohol use …

Almost every neurological disease directly or indirectly affects synapse function in the brain.
However, these diseases alter synapses through different mechanisms, ultimately resulting …

Alcohol is one of the most widely used substances. Alcohol use accounts for 5.1% of the
global disease burden, contributes substantially to societal and economic costs, and leads …

Excessive alcohol use is associated with a wide range of physical, psychological and social
consequences, and is responsible for a significant proportion of the burden of disease …

Abstract β‐Phenyl‐γ‐aminobutyric acid (phenibut) is an analog of the inhibitory
neurotransmitter γ‐aminobutyric acid (GABA) that was first synthesized in Russia in the early …