Polymeric delivery of therapeutic nucleic acids

R Kumar, CF Santa Chalarca, MR Bockman… - Chemical …, 2021 - ACS Publications
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

Molecular interactions driving the layer-by-layer assembly of multilayers

J Borges, JF Mano - Chemical reviews, 2014 - ACS Publications
Over the last few decades there has been a huge interest in nanostructured functional
materials and assembly techniques for preparing functional molecular assemblies with …

Electrochemical nanoarchitectonics and layer-by-layer assembly: From basics to future

G Rydzek, Q Ji, M Li, P Schaaf, JP Hill, F Boulmedais… - Nano Today, 2015 - Elsevier
During the last few decades, electrochemistry and electrode modification have seen a
tremendous fall off in creativity with the emergence of the nanoarchitectonic-based layer-by …

Responsive layer-by-layer materials for drug delivery

BM Wohl, JFJ Engbersen - Journal of controlled release, 2012 - Elsevier
Due to its versatility and ease of use the layer-by-layer (LbL) assembly technique has been
under intensive investigation for drug and gene delivery applications. Especially the …

pH-and sugar-sensitive layer-by-layer films and microcapsules for drug delivery

K Sato, K Yoshida, S Takahashi, J Anzai - Advanced drug delivery reviews, 2011 - Elsevier
The present review provides an overview on the recent progress in the development of pH-
and sugar-sensitive layer-by-layer (LbL) thin films and microcapsules in relation to their …

An influenza virus-inspired polymer system for the timed release of siRNA

NP Truong, W Gu, I Prasadam, Z Jia, R Crawford… - Nature …, 2013 - nature.com
Small interfering RNA silences specific genes by interfering with mRNA translation, and acts
to modulate or inhibit specific biological pathways; a therapy that holds great promise in the …

Layered self-assemblies for controlled drug delivery: A translational overview

A Sarode, A Annapragada, J Guo, S Mitragotri - Biomaterials, 2020 - Elsevier
Self-assembly is a prominent phenomenon observed in nature. Inspired by this
thermodynamically favorable approach, several natural and synthetic materials have been …

Layer‐by‐layer assembly of light‐responsive polymeric multilayer systems

J Borges, LC Rodrigues, RL Reis… - Advanced Functional …, 2014 - Wiley Online Library
Layer‐by‐Layer (LbL) assembly is a simple and highly versatile method to modify surfaces
and fabricate robust and highly‐ordered nanostructured coatings over almost any type of …

Electrically triggered release of a small molecule drug from a polyelectrolyte multilayer coating

DJ Schmidt, JS Moskowitz, PT Hammond - Chemistry of Materials, 2010 - ACS Publications
Electrically triggered drug delivery represents an attractive option for actively and remotely
controlling the release of a therapeutic from an implantable device (eg, a “pharmacy-on-a …

Spatio‐temporal control of LbL films for biomedical applications: from 2D to 3D

C Monge, J Almodóvar, T Boudou… - Advanced healthcare …, 2015 - Wiley Online Library
Introduced in the'90s by Prof. Moehwald, Lvov, and Decher, the layer‐by‐layer (LbL)
assembly of polyelectrolytes has become a popular technique to engineer various types of …