Buccal delivery of small and large molecules is an attractive route of administration that has
been studied extensively over the past few decades. This route bypasses first-pass …

Understanding and establishing a link between the physicochemical characteristics of
nanoparticles (NPs) and their biological interactions poses to be a great challenge in the …

The greatest achievement in the advanced drug delivery field should be the optimization of
non-invasive formulations for the delivery of high molecular weight compounds. Peptides …

Hydrogels are hydrophilic, three-dimensional, cross-linked polymers that absorb significant
amounts of biological fluids or water. Hydrogels possess several favorable properties …

Due to its numerous advantages, such as excellent drug accessibility, rapid absorption, and
bypass of first-pass metabolism, the route of drug administration that involves crossing the …

Oral diseases rank among the most widespread ailments worldwide posing significant
global health and economic challenges affecting around 3.5 billion people, impacting the …

This research aimed to develop miconazole-based microemulsions using oleic acid as a
natural lipophilic phase and a stabilizer mixture comprising Tween 20 and PEG 400 to …

Gingiva or gum is a part of the periodontium that surrounds the tooth. Its main function is to
provide an effective barrier to both mechanical trauma and bacterial invasion. Gingiva is the …

The main objective of this study is the evaluation of the use of a synthetic membrane,
Nuclepore, as a model for permeation studies through sublingual mucosa. The permeability …

Oromucosal drug delivery, both local and transmucosal (buccal), is an effective alternative to
traditional oral and parenteral dosage forms because it increases drug bioavailability and …