Intracerebral haemorrhage is inadequately controlled by current treatments, requiring new
solutions to improve the prognosis. Following the primary injury, a proinflammatory cascade …

Intracerebral hemorrhage (ICH) has one of the worst prognoses among patients with stroke.
Surgical measures have been adopted to relieve the mass effect of the hematoma, and …

The pathological role of reactive gliosis in CNS repair remains controversial. In this study,
using murine ischemic and hemorrhagic stroke models, we demonstrated that microglia …

Zinc is one of the most abundant metal ions in the central nervous system (CNS), where it
plays a crucial role in both physiological and pathological brain functions. Zinc promotes …

Spinal cord injury (SCI) causes immune activation of resident macrophages/microglia.
Activated macrophages/microglia have two different phenotypes, the pro-inflammatory …

Intracerebral haemorrhage (ICH) is the second most common type of stroke and a major
cause of mortality and disability worldwide. Despite advances in surgical interventions and …

Intracerebral hemorrhage (ICH) is a highly fatal disease with mortality rate of approximately
50%. Oxidative stress (OS) is a prominent cause of brain injury in ICH. Important sources of …

The spleen, an important tissue for the immune system, acts as a filter for blood within the
immune system. Accumulating evidence suggests that the spleen affects a number of brain …

Poor prognosis is often expected after the treatment of intracerebral haemorrhage (ICH)
when the approach lacks effective neuroprotective interventions. Minocycline (Mino) is a …

Angiogenesis, the growth of new blood vessels, is a natural defense mechanism helping to
restore oxygen and nutrient supply to the affected brain tissue following an ischemic stroke …