Novel benzothiazole/benzothiazole thiazolidine‐2, 4‐dione derivatives as potential FOXM1 inhibitors: In silico, synthesis, and in vitro studies
KAN Abusharkh, F Comert Onder, V Çınar… - Archiv der …, 2024 - Wiley Online Library
The oncogenic transcription factor FOXM1 overexpressed in breast and other solid cancers,
is a key driver of tumor growth and progression through complex interactions, making it an …
is a key driver of tumor growth and progression through complex interactions, making it an …
Synthesis, molecular docking and ADME studies of thiazole-thiazolidinedione hybrids as antimicrobial agents
SG Alegaon, VU, KR Alagawadi, D Kumar… - Journal of …, 2022 - Taylor & Francis
New thiazole-thiazolidinedione hybrids (5a–k) were efficiently synthesized and evaluated for
their in-vitro antimicrobial activity against four fungal and bacterial strains. The chemical …
their in-vitro antimicrobial activity against four fungal and bacterial strains. The chemical …
Design, synthesis, molecular docking and ADME studies of novel indole-thiazolidinedione derivatives and their antineoplastic activity as CDK6 inhibitors
Z Ates-Alagoz, MM Kisla, FZ Karadayi… - New Journal of …, 2021 - pubs.rsc.org
Several 5-((5-substituted-1H-indole-3-yl) methylene)-3-(2-oxo-2-(3/4-substituted-
phenylethyl)-thiazolidine-2, 4-dione derivatives (9–24) were designed and synthesized as …
phenylethyl)-thiazolidine-2, 4-dione derivatives (9–24) were designed and synthesized as …
One-pot synthesis of novel 2-imino-5-arylidine-thiazolidine analogues and evaluation of their anti-proliferative activity against MCF7 breast cancer cell line
An efficient surface-mediated synthetic method to facilitate access to a novel class of
thiazolidines is described. The rationale behind the design of the targeted thiazolidines was …
thiazolidines is described. The rationale behind the design of the targeted thiazolidines was …
Combined effects of pioglitazone and doxorubicin on migration and invasion of MDA-MB-231 breast cancer cells
Background Despite antitumor properties, chemotherapy medication can create conditions
in tumor cells that work in favor of the tumor. Doxorubicin, commonly prescribed …
in tumor cells that work in favor of the tumor. Doxorubicin, commonly prescribed …