Fibromyalgia: pathogenesis, mechanisms, diagnosis and treatment options update

R Siracusa, RD Paola, S Cuzzocrea… - International journal of …, 2021 - mdpi.com
Fibromyalgia is a syndrome characterized by chronic and widespread musculoskeletal pain,
often accompanied by other symptoms, such as fatigue, intestinal disorders and alterations …

Neurobiology of fibromyalgia and chronic widespread pain

KA Sluka, DJ Clauw - Neuroscience, 2016 - Elsevier
Fibromyalgia is the current term for chronic widespread musculoskeletal pain for which no
alternative cause can be identified. The underlying mechanisms, in both human and animal …

Exercise-induced pain and analgesia? Underlying mechanisms and clinical translation

KA Sluka, L Frey-Law, MH Bement - Pain, 2018 - journals.lww.com
Physical inactivity or a sedentary lifestyle is a significant health concern worldwide. The
Centers for Disease Control (CDC) recommends 150 minutes per week of moderate to …

Is fibromyalgia associated with a unique cytokine profile? A systematic review and meta-analysis

LF O'Mahony, A Srivastava, P Mehta, C Ciurtin - Rheumatology, 2021 - academic.oup.com
Objectives The aetiology of primary chronic pain syndromes (CPS) is highly disputed. We
performed a systematic review and meta-analysis aiming to assess differences in circulating …

Role of inflammation in the pathogenesis and treatment of fibromyalgia

I Coskun Benlidayi - Rheumatology international, 2019 - Springer
Fibromyalgia is a multifaceted disease. The clinical picture of fibromyalgia covers numerous
comorbidities. Each comorbidity stands as a distinct condition. However, common …

Chronic pain in musculoskeletal diseases: Do you know your enemy?

R Bonanni, I Cariati, V Tancredi, R Iundusi… - Journal of clinical …, 2022 - mdpi.com
Musculoskeletal pain is a condition that characterises several diseases and represents a
constantly growing issue with enormous socio-economic burdens, highlighting the …

Neurogenic inflammation in fibromyalgia

G Littlejohn, E Guymer - Seminars in immunopathology, 2018 - Springer
Fibromyalgia is a high impact chronic pain disorder with a well-defined and robust clinical
phenotype. Key features include widespread pain and tenderness, high levels of sleep …

Oxidative stress in fibromyalgia: from pathology to treatment

C Assavarittirong, W Samborski… - … Medicine and Cellular …, 2022 - Wiley Online Library
Fibromyalgia (FM) is characterized by chronic widespread musculoskeletal pain associated
with sleep problems, fatigue, depression, and anxiety. The persistence of pain, impairment …

[HTML][HTML] Fibromyalgia and depression: a literature review of their shared aspects

D Yepez, XA Grandes, RT Manjunatha, S Habib… - Cureus, 2022 - ncbi.nlm.nih.gov
Fibromyalgia (FM) is a chronic pain syndrome characterized by widespread, persistent pain
that lasts more than three months without an evident organic lesion. FM has been …

The role of the vagus nerve in fibromyalgia syndrome

DF Martins, FJF Viseux, DC Salm, ACA Ribeiro… - Neuroscience & …, 2021 - Elsevier
Fibromyalgia (FM) syndrome is a common illness characterized by chronic widespread pain,
sleep problems, fatigue, and cognitive difficulties. Dysfunctional neurotransmitter systems …