In past years, microneedle (MN)-mediated transdermal drug delivery has paved a new way
for cancer therapy. MN is a local drug delivery method that can reduce systemic drug …

The limitations of conventional therapeutic treatments prevailed in the development of
nanotechnology-based medical formulations, termed nanomedicine. Nanomedicine is an …

Internal lubrication with magnesium stearate (MgSt) is associated with a reduced tensile
strength and prolonged disintegration and dissolution times. In the current study, alternative …

Probiotic microorganisms provide health benefits to the patient when administered in a
viable form and in sufficient doses. To ensure this, dry dosage forms are preferred, with …

The magnitude of the frictional forces during the ejection of porous pharmaceutical tablets
plays an important role in determining the occurrence of tabletting defects. Here, we perform …

Modeling of structural and mechanical tablet properties consisting of multiple components,
based on a minimum of experimental data is of high interest, in order to minimize time-and …

Tablets are the favored dosage form for numerous active pharmaceutical ingredients,
among others because they are easy to take, ensure safe dosing and allow cost-effective …

In rotary tablet presses, the powder flow into the dies is typically facilitated by paddle feeder.
For internally lubricated formulations, the shear forces exerted by the paddle rotation can …

Tensile strength (TS), solid fraction (SF), and tablet weight variability (TWV) are all key
quality factors to be considered during the tablet manufacturing process. For predicting …

Significant improvements in the wettability and dissolution rate of celecoxib (CEL), a poorly
soluble selective cyclooxygenase-2 (COX-2) inhibitor, have been shown by Huyn et al …