Ghrelin, CCK, GLP-1, and PYY (3–36): secretory controls and physiological roles in eating and glycemia in health, obesity, and after RYGB
The efficacy of Roux-en-Y gastric-bypass (RYGB) and other bariatric surgeries in the
management of obesity and type 2 diabetes mellitus and novel developments in …
management of obesity and type 2 diabetes mellitus and novel developments in …
The cellular and molecular bases of leptin and ghrelin resistance in obesity
Obesity, a major risk factor for the development of diabetes mellitus, cardiovascular diseases
and certain types of cancer, arises from a chronic positive energy balance that is often due to …
and certain types of cancer, arises from a chronic positive energy balance that is often due to …
[HTML][HTML] Ghrelin
Background The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the
endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence …
endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence …
Antibiotic perturbation of the murine gut microbiome enhances the adiposity, insulin resistance, and liver disease associated with high-fat diet
Background Obesity, type 2 diabetes, and non-alcoholic fatty liver disease (NAFLD) are
serious health concerns, especially in Western populations. Antibiotic exposure and high-fat …
serious health concerns, especially in Western populations. Antibiotic exposure and high-fat …
Obesity impairs the action of the neuroendocrine ghrelin system
Ghrelin is a metabolic hormone that promotes energy conservation by regulating appetite
and energy expenditure. Although some studies suggest that antagonizing ghrelin function …
and energy expenditure. Although some studies suggest that antagonizing ghrelin function …
Blood-brain barriers in obesity
EM Rhea, TS Salameh, AF Logsdon, AJ Hanson… - The AAPS journal, 2017 - Springer
After decades of rapid increase, the rate of obesity in adults in the USA is beginning to slow
and the rate of childhood obesity is stabilizing. Despite these improvements, the obesity …
and the rate of childhood obesity is stabilizing. Despite these improvements, the obesity …
Ghrelin deletion and conditional ghrelin cell ablation increase pancreatic islet size in mice
Ghrelin exerts key effects on islet hormone secretion to regulate blood glucose levels. Here,
we sought to determine whether ghrelin's effects on islets extend to the alteration of islet size …
we sought to determine whether ghrelin's effects on islets extend to the alteration of islet size …
[HTML][HTML] Regulation of body weight: lessons learned from bariatric surgery
Background Bariatric or weight loss surgery is currently the most effective treatment for
obesity and metabolic disease. Unlike dieting and pharmacology, its beneficial effects are …
obesity and metabolic disease. Unlike dieting and pharmacology, its beneficial effects are …
Ghrelin's relationship to blood glucose
Much effort has been directed at studying the orexigenic actions of administered ghrelin and
the potential effects of the endogenous ghrelin system on food intake, food reward, body …
the potential effects of the endogenous ghrelin system on food intake, food reward, body …
[HTML][HTML] Ghrelin–physiological functions and regulation
MMI Abdalla - European endocrinology, 2015 - ncbi.nlm.nih.gov
Ghrelin is an orexigenic peptide predominantly secreted from the stomach and stimulates
appetite and growth hormone (GH) release. Studies have provided evidence that ghrelin …
appetite and growth hormone (GH) release. Studies have provided evidence that ghrelin …