Activated pancreatic stellate cells (PSCs) are the main effector cells in the process of
fibrosis, a major pathological feature in pancreatic diseases that including chronic …

Pancreatic fibrosis is a characteristic feature of chronic pancreatitis and of desmoplastic
reaction associated with pancreatic cancer. For over a decade, there has been accumulating …

Myofibroblasts are critical cellular elements of wound healing generated at sites of injury by
transdifferentiation of resident cells. A paradigm for this process is conversion of hepatic …

BACKGROUND Endometriosis is a benign gynaecological disease. Thus, it came as a
complete surprise when it was reported recently that the majority of deep endometriosis …

Until now, no specific therapies are available to inhibit pancreatic fibrosis, a constant
pathological feature of chronic pancreatitis and pancreatic cancer. One major reason is the …

An estrogen dependency has been suggested for the growth of fibroadenomas: however,
thus far, none of the steroid hormone receptors acting on breast tissues has been …

Stellate cells are vitamin A-storing cells of liver and pancreas and have been described in all
vertebrates ranging from lampreys (primitive fish) to humans, demonstrating their major …

Pluripotent pancreatic stellate cells (PSCs) receive growing interest in past decades. Two
types of PSCs are recognized–vitamin A accumulating quiescent PSCs and activated PSCs …

The appearance of myofibroblasts is generally thought to be the underlying cause of the
fibrotic changes that underlie idiopathic pulmonary fibrosis. However, the cellular/molecular …

Chronic pancreatitis is characterized by chronic inflammation and fibrosis, processes
heightened by activated pancreatic stellate cells (PSCs). Recent publications have …