Abstract Heme oxygenase (HO)-1, the inducible isoform of the heme-degrading enzyme HO,
plays a critical role in inflammation and iron homeostasis. Regulatory functions of HO-1 are …

The heme oxygenases, which consist of constitutive and inducible isozymes (HO-1, HO-2),
catalyze the rate-limiting step in the metabolic conversion of heme to the bile pigments (ie …

Heme oxygenase (HO)-1 is the inducible isoform of the first and rate-limiting enzyme of
heme degradation. Induction of HO-1 protects against the cytotoxicity of oxidative stress and …

The ability to communicate with the environment and respond to changes—particularly
those of an adverse nature—within that environment is critical for cell function and survival …

The ubiquitous gas, carbon monoxide (CO), is of substantial biological importance, but apart
from its affinity for reduced transition metals, particularly heme-iron, it is surprisingly …

Heme oxygenase (HO), the rate limiting enzyme in the breakdown of heme into carbon
monoxide (CO), iron and bilirubin, has recently received overwhelming research attention …

The impact of nanoparticles (NPs) in medicine and biology has increased rapidly in recent
years. Gold NPs have advantageous properties such as chemical stability, high electron …

Heme oxygenase (HO)-1, involved in the heme degradation process, is an important
antioxidant enzyme. The induction of HO-1 gene expression, in response to diverse …

Dengue virus (DENV) infection and replication induces oxidative stress, which further
contributes to the progression and pathogenesis of the DENV infection. Modulation of host …

Cigarette smoking is a significant environmental factor in the human inflammatory bowel
diseases, remarkably, conferring protection in ulcerative colitis. We previously demonstrated …