Metabolic (dysfunction)-associated fatty liver disease in individuals of normal weight

M Eslam, HB El-Serag, S Francque, SK Sarin… - Nature reviews …, 2022 - nature.com
Metabolic (dysfunction)-associated fatty liver disease (MAFLD) affects up to a third of the
global population; its burden has grown in parallel with rising rates of type 2 diabetes …

The EASL–Lancet Liver Commission: protecting the next generation of Europeans against liver disease complications and premature mortality

TH Karlsen, N Sheron, S Zelber-Sagi, P Carrieri… - The Lancet, 2022 - thelancet.com
Executive summary Liver diseases have become a major health threat across Europe, and
the face of European hepatology is changing due to the cure of viral hepatitis C and the …

Global multi-stakeholder endorsement of the MAFLD definition

N Méndez-Sánchez, E Bugianesi, RG Gish… - The lancet …, 2022 - thelancet.com
Correspondence 390 www. thelancet. com/gastrohep Vol 7 May 2022 at least two different
mechanisms of action. Views were divided on the failure of immunomodulators, with 252 …

[HTML][HTML] MAFLD: How is it different from NAFLD?

C Gofton, Y Upendran, MH Zheng… - Clinical and molecular …, 2023 - ncbi.nlm.nih.gov
Abstract “Metabolic dysfunction-associated fatty liver disease (MAFLD)” is the term
suggested in 2020 to refer to fatty liver disease related to systemic metabolic dysregulation …

Non-alcoholic fatty liver disease: a multisystem disease requiring a multidisciplinary and holistic approach

G Targher, H Tilg, CD Byrne - The lancet Gastroenterology & …, 2021 - thelancet.com
Non-alcoholic fatty liver disease (NAFLD) is a public health problem worldwide. This
narrative Review provides an overview of the current literature to support the notion that …

Defining paediatric metabolic (dysfunction)-associated fatty liver disease: an international expert consensus statement

M Eslam, N Alkhouri, P Vajro, U Baumann… - The Lancet …, 2021 - thelancet.com
The term non-alcoholic fatty liver disease (NAFLD), and its definition, have limitations for
both adults and children. The definition is most problematic for children, for whom alcohol …

Differential clinical characteristics and mortality outcomes in persons with NAFLD and/or MAFLD

VH Nguyen, MH Le, RC Cheung, MH Nguyen - Clinical Gastroenterology …, 2021 - Elsevier
Background & aims Metabolic dysfunction–associated fatty liver disease (MAFLD)
establishes new criteria for diagnosing fatty liver disease independent of alcohol intake and …

Intestinal barrier and permeability in health, obesity and NAFLD

P Portincasa, L Bonfrate, M Khalil, MD Angelis… - Biomedicines, 2021 - mdpi.com
The largest surface of the human body exposed to the external environment is the gut. At this
level, the intestinal barrier includes luminal microbes, the mucin layer, gastrointestinal …

Mechanisms of non-alcoholic fatty liver disease in the metabolic syndrome. A narrative review

L Rinaldi, PC Pafundi, R Galiero, A Caturano… - Antioxidants, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS) are two different
entities sharing common clinical and physio-pathological features, with insulin resistance …

The Chinese Society of Hepatology position statement on the redefinition of fatty liver disease

Y Nan, J An, J Bao, H Chen, Y Chen, H Ding, X Dou… - Journal of …, 2021 - Elsevier
Fatty liver disease associated with metabolic dysfunction is of increasing concern in
mainland China, the world's most populous country. The incidence of fatty liver disease is …