K Brindle - Nature Reviews Cancer, 2008 - nature.com
Tumour responses to treatment are still largely assessed from imaging measurements of reductions in tumour size. However, this can take several weeks to become manifest and in …
L Gonzalez, BL Trigatti - Canadian Journal of Cardiology, 2017 - Elsevier
Cardiovascular diseases represent 1 of the main causes of death worldwide, and atherosclerosis is 1 of the major contributors leading to ischemic heart disease …
FG Blankenberg - Journal of Nuclear Medicine, 2008 - Soc Nuclear Med
After several decades of debate, it is now widely acknowledged that apoptosis, also known as programmed cell death, is central to homoeostasis and normal development and …
BM Zeglis, C Brand, D Abdel-Atti… - Molecular …, 2015 - ACS Publications
Pretargeted PET imaging has emerged as an effective strategy for merging the exquisite selectivity of antibody-based targeting vectors with the rapid pharmacokinetics of …
BA Smith, BD Smith - Bioconjugate chemistry, 2012 - ACS Publications
Cell death is a critically important biological process. Disruption of homeostasis, either by excessive or deficient cell death, is a hallmark of many pathological conditions. Recent …
N Viola-Villegas, RP Doyle - Coordination Chemistry Reviews, 2009 - Elsevier
1, 4, 7, 10-Tetraazacyclododecane-N, N′, N ″, N′″-tetraacetic acid (DOTA) is one of the preeminent carriers of metal-based radiopharmaceutics and imaging contrast agents. This …
W Zeng, X Wang, P Xu, G Liu, HS Eden, X Chen - Theranostics, 2015 - ncbi.nlm.nih.gov
Apoptosis, or programmed cell death, is involved in numerous human conditions including neurodegenerative diseases, ischemic damage, autoimmune disorders and many types of …
Enzyme Linked Immunosorbent Assay (ELISA) is the gold standard assay for detecting and identifying biomolecules using antibodies as the probe. Improving ELISA is crucial for …
PET is an exquisitely sensitive molecular imaging technique using positron-emitting radioisotopes coupled to specific ligands. Many biological targets of great interest can be …