Imaging and photodynamic therapy: mechanisms, monitoring, and optimization

JP Celli, BQ Spring, I Rizvi, CL Evans… - Chemical …, 2010 - ACS Publications
The purpose of this review is to present the current state of the role of imaging in
photodynamic therapy (PDT). For the reader to fully appreciate the context of the discussions …

New approaches for imaging tumour responses to treatment

K Brindle - Nature Reviews Cancer, 2008 - nature.com
Tumour responses to treatment are still largely assessed from imaging measurements of
reductions in tumour size. However, this can take several weeks to become manifest and in …

Macrophage apoptosis and necrotic core development in atherosclerosis: a rapidly advancing field with clinical relevance to imaging and therapy

L Gonzalez, BL Trigatti - Canadian Journal of Cardiology, 2017 - Elsevier
Cardiovascular diseases represent 1 of the main causes of death worldwide, and
atherosclerosis is 1 of the major contributors leading to ischemic heart disease …

In vivo detection of apoptosis

FG Blankenberg - Journal of Nuclear Medicine, 2008 - Soc Nuclear Med
After several decades of debate, it is now widely acknowledged that apoptosis, also known
as programmed cell death, is central to homoeostasis and normal development and …

Optimization of a pretargeted strategy for the PET imaging of colorectal carcinoma via the modulation of radioligand pharmacokinetics

BM Zeglis, C Brand, D Abdel-Atti… - Molecular …, 2015 - ACS Publications
Pretargeted PET imaging has emerged as an effective strategy for merging the exquisite
selectivity of antibody-based targeting vectors with the rapid pharmacokinetics of …

Biomarkers and molecular probes for cell death imaging and targeted therapeutics

BA Smith, BD Smith - Bioconjugate chemistry, 2012 - ACS Publications
Cell death is a critically important biological process. Disruption of homeostasis, either by
excessive or deficient cell death, is a hallmark of many pathological conditions. Recent …

The coordination chemistry of 1, 4, 7, 10-tetraazacyclododecane-N, N′, N ″, N′″-tetraacetic acid (H4DOTA): Structural overview and analyses on structure …

N Viola-Villegas, RP Doyle - Coordination Chemistry Reviews, 2009 - Elsevier
1, 4, 7, 10-Tetraazacyclododecane-N, N′, N ″, N′″-tetraacetic acid (DOTA) is one of the
preeminent carriers of metal-based radiopharmaceutics and imaging contrast agents. This …

[HTML][HTML] Molecular imaging of apoptosis: from micro to macro

W Zeng, X Wang, P Xu, G Liu, HS Eden, X Chen - Theranostics, 2015 - ncbi.nlm.nih.gov
Apoptosis, or programmed cell death, is involved in numerous human conditions including
neurodegenerative diseases, ischemic damage, autoimmune disorders and many types of …

Biotin-streptavidin competition mediates sensitive detection of biomolecules in enzyme linked immunosorbent assay

T Lakshmipriya, SCB Gopinath, TH Tang - PLoS One, 2016 - journals.plos.org
Enzyme Linked Immunosorbent Assay (ELISA) is the gold standard assay for detecting and
identifying biomolecules using antibodies as the probe. Improving ELISA is crucial for …

Non-[18F] FDG PET in clinical oncology

AM Groves, T Win, SB Haim, PJ Ell - The lancet oncology, 2007 - thelancet.com
PET is an exquisitely sensitive molecular imaging technique using positron-emitting
radioisotopes coupled to specific ligands. Many biological targets of great interest can be …