Modulation of transient receptor potential (TRP) channels by plant derived substances used in over-the-counter cough and cold remedies

RJ Stinson, AH Morice, LR Sadofsky - Respiratory Research, 2023 - Springer
Background Upper respiratory tract infections (URTIs) impact all age groups and have a
significant economic and social burden on society, worldwide. Most URTIs are mild and self …

Protective effects of natural antioxidants on inflammatory bowel disease: thymol and its pharmacological properties

Y Liu, H Yan, B Yu, J He, X Mao, J Yu, P Zheng… - Antioxidants, 2022 - mdpi.com
Inflammatory bowel disease (IBD) is a gastrointestinal disease that involves chronic mucosal
or submucosal lesions that affect tissue integrity. Although IBD is not life-threatening, it …

Hesperidin has a protective effect on paclitaxel-induced testicular toxicity through regulating oxidative stress, apoptosis, inflammation and endoplasmic reticulum …

M Ileriturk, O Kandemir, N Akaras, H Simsek… - Reproductive …, 2023 - Elsevier
Paclitaxel (PTX) is widely used to treat a number of malignancies, although it has toxic side
effects. Hesperidin (HES) has a wide range of biological and pharmacological properties …

Investigation of the effects of hesperidin administration on abamectin‐induced testicular toxicity in rats through oxidative stress, endoplasmic reticulum stress …

C Gur, O Kandemir, FM Kandemir - Environmental Toxicology, 2022 - Wiley Online Library
In this study, the potential effects of hesperidin (HES) on chronic toxicity caused by
abamectin (ABM) in the testicular tissue were investigated through oxidative stress …

The protective effects of hesperidin against paclitaxel-induced peripheral neuropathy in rats

HS Semis, FM Kandemir, O Kaynar, T Dogan… - Life Sciences, 2021 - Elsevier
Paclitaxel (PTX), which is widely used in the treatment of solid tumors, leads to dose
limitation because it causes peripheral neuropathy. This study was conducted to evaluate …

Naringin and Hesperidin Counteract Diclofenac‐Induced Hepatotoxicity in Male Wistar Rats via Their Antioxidant, Anti‐Inflammatory, and Antiapoptotic Activities

RA Hassan, WG Hozayen, HT Abo Sree… - Oxidative medicine …, 2021 - Wiley Online Library
This study is aimed at evaluating the preventive effect and at suggesting the mode of actions
of naringin and hesperidin and their combination in diclofenac‐induced hepatotoxicity. Male …

Apigenin attenuates inflammatory response in allergic rhinitis mice by inhibiting the TLR4/MyD88/NF‐κB signaling pathway

H Li, H Zhang, H Zhao - Environmental Toxicology, 2023 - Wiley Online Library
Background Allergic rhinitis (AR) is an immunoglobulin E (IgE)‐mediated immune
inflammatory response that mainly affects the nasal mucosa. Currently, there is evidence …

[HTML][HTML] Gleditsia sinensis Lam. aqueous extract attenuates nasal inflammation in allergic rhinitis by inhibiting MUC5AC production through suppression of the STAT3 …

MA Jung, HK Song, K Jo, A Lee, YH Hwang… - Biomedicine & …, 2023 - Elsevier
Allergic rhinitis (AR), a chronic respiratory inflammatory disease, is among the most common
chronic diseases reported worldwide. Mucus hypersecretion is a critical feature of AR …

Chitosan hydrogel doped with PEG-PLA nanoparticles for the local delivery of miRNA-146a to treat allergic rhinitis

Y Su, B Sun, X Gao, S Liu, R Hao, B Han - Pharmaceutics, 2020 - mdpi.com
To prepare a binary formulation delivering miRNA-146 and evaluate a nucleic acid nasal
delivery system by investigating its pharmacodynamic effects in allergic rhinitis. The …

A systematic review and meta‐analysis of the effect of thymol as an anti‐inflammatory and wound healing agent: A review of thymol effect on inflammation and wound …

PR Gabbai‐Armelin, LS Sales, TM Ferrisse… - Phytotherapy …, 2022 - Wiley Online Library
Thymol (THY) exhibits antibacterial and antioxidant properties. Recent studies have also
shown that THY presents anti‐inflammatory and healing properties. This review focused on …