Research on the neurobiology of the kynurenine pathway has suffered years of relative
obscurity because tryptophan degradation, and its involvement in both physiology and major …

Ionotropic glutamate receptors are composed of homomeric or heteromeric configurations of
glutamate receptor subunits. We have cloned a member of a novel class of the rat ionotropic …

As a major metabolite of kynurenine in the oxidative metabolism of tryptophan, kynurenic
acid is of considerable biological and clinical importance as an endogenous antagonist of …

In this article, the beginnings of glutamate pharmacology are traced from the early doubts
about 'non-specific'excitatory effects, through glutamate-and aspartate-preferring receptors …

The effects of ethanol on the binding of [3 H] MK-801,[3 H] l-glutamate,[3 H] glycine and [3 H]
CGS 19755 to the N-methyl-d-aspartate receptor were determined in membranes from …

The amino acid D‐serine (D‐Ser), previously recognized as a pharmacological tool for
potentiating neuronal activity mediated by the N‐methyl‐D‐aspartate (NMDA) receptor …

In the 1960s and 70s, biochemical and pharmacological evidence was pointing toward
glutamate as a synaptic transmitter at a number of distinct receptor classes, known as NMDA …

The pharmacology of recombinant NR1a/NR2D NMDA receptors expressed in Xenopus
oocytes was examined and compared to the pharmacology of NR1a/NR2A, NR1a/NR2B …

The Ionotropic Glutamate Receptors provides the first detailed survey of the biochemical,
physiological, and pharmacological properties of recombinant ionotropic glutamate …

Glutamate receptors continued to be the subject of intense investigation during 1992. It is
clear that there is great structural and functional diversity within this receptor family, although …