Glycosylation: mechanisms, biological functions and clinical implications

M He, X Zhou, X Wang - Signal Transduction and Targeted Therapy, 2024 - nature.com
Protein post-translational modification (PTM) is a covalent process that occurs in proteins
during or after translation through the addition or removal of one or more functional groups …

Glutathione in cancer biology and therapy

JM Estrela, A Ortega, E Obrador - Critical reviews in clinical …, 2006 - Taylor & Francis
The glutathione (GSH) content of cancer cells is particularly relevant in regulating mutagenic
mechanisms, DNA synthesis, growth, and multidrug and radiation resistance. In malignant …

Expression of CC chemokine receptor-7 and regional lymph node metastasis of B16 murine melanoma

HE Wiley, EB Gonzalez, W Maki, M Wu… - Journal of the …, 2001 - academic.oup.com
Abstract Background: CC chemokine receptor-7 (CCR7), which plays a critical role in the
migration of activated dendritic cells to regional lymph nodes via afferent lymphatic vessels …

IL-18 regulates IL-1β-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1

F Vidal-Vanaclocha, G Fantuzzi… - Proceedings of the …, 2000 - National Acad Sciences
Proinflammatory cytokines, including IL-1 β and tumor necrosis factor-α (TNF-α), promote
cancer cell adhesion and liver metastases by up-regulating the expression of vascular cell …

On the role of cell surface carbohydrates and their binding proteins (lectins) in tumor metastasis

E Gorelik, U Galili, A Raz - Cancer and Metastasis Reviews, 2001 - Springer
This review focuses on the recent advances in investigations of the role of cell surface
carbohydrates in tumor metastasis. It also summarizes the results of extensive studies of …

Systemic inflammation increases cancer cell adhesion to hepatic sinusoids by neutrophil mediated mechanisms

B McDonald, J Spicer, B Giannais… - … journal of cancer, 2009 - Wiley Online Library
Interactions between endothelial selectins and selectin ligands expressed on tumor cells
have been implicated in the binding of circulating metastatic cancer cells to the vascular …

Candida albicans and cancer: Can this yeast induce cancer development or progression?

A Ramirez-Garcia, A Rementeria… - Critical reviews in …, 2016 - Taylor & Francis
There is currently increasing concern about the relation between microbial infections and
cancer. More and more studies support the view that there is an association, above all, when …

Interactions between cancer cells and the endothelium in metastasis

FW Orr, HH Wang, RM Lafrenie… - The Journal of …, 2000 - Wiley Online Library
The haematogenous phase of cancer metastasis facilitates the transport of metastatic cells
within the blood and incorporates a sequence of interactions between circulating …

Association between pterostilbene and quercetin inhibits metastatic activity of B16 melanoma

P Ferrer, M Asensi, R Segarra, A Ortega, M Benlloch… - Neoplasia, 2005 - Elsevier
Inhibition of cancer growth by resveratrol (trans-3, 5, 4'trihydroxystilbene; RESV), a
phytoalexin present in many plant species, is limited by its low bioavailability. Pterostilbene …

Growth-associated changes in glutathione content correlate with liver metastatic activity of B16 melanoma cells

J Carretero, E Obrador, MJ Anasagasti… - Clinical & experimental …, 1999 - Springer
Abstract B16 melanoma (B16M) was used to study the relationship between glutathione
(GSH) metabolism and the metastatic acitivity of malignant cells. GSH content increased in …