Insulin-like peptides and cross-talk with other factors in the regulation of insect metabolism

S Chowański, K Walkowiak-Nowicka, M Winkiel… - Frontiers in …, 2021 - frontiersin.org
The insulin-like peptide (ILP) and insulin-like growth factor (IGF) signalling pathways play a
crucial role in the regulation of metabolism, growth and development, fecundity, stress …

Sleep deprivation and central appetite regulation

S Liu, X Wang, Q Zheng, L Gao, Q Sun - Nutrients, 2022 - mdpi.com
Research shows that reduced sleep duration is related to an increased risk of obesity. The
relationship between sleep deprivation and obesity, type 2 diabetes, and other chronic …

The sugar-responsive enteroendocrine neuropeptide F regulates lipid metabolism through glucagon-like and insulin-like hormones in Drosophila melanogaster

Y Yoshinari, H Kosakamoto, T Kamiyama… - Nature …, 2021 - nature.com
The enteroendocrine cell (EEC)-derived incretins play a pivotal role in regulating the
secretion of glucagon and insulins in mammals. Although glucagon-like and insulin-like …

N6-adenosine methylation controls the translation of insulin mRNA

D Wilinski, M Dus - Nature Structural & Molecular Biology, 2023 - nature.com
Control of insulin mRNA translation is crucial for energy homeostasis, but the mechanisms
remain largely unknown. We discovered that insulin mRNAs across invertebrates …

Hormonal axes in Drosophila: regulation of hormone release and multiplicity of actions

DR Nässel, M Zandawala - Cell and tissue research, 2020 - Springer
Hormones regulate development, as well as many vital processes in the daily life of an
animal. Many of these hormones are peptides that act at a higher hierarchical level in the …

[HTML][HTML] Visceral mechano-sensing neurons control Drosophila feeding by using Piezo as a sensor

P Wang, Y Jia, T Liu, YN Jan, W Zhang - Neuron, 2020 - cell.com
Animal feeding is controlled by external sensory cues and internal metabolic states. Does it
also depend on enteric neurons that sense mechanical cues to signal fullness of the …

What fuels the fly: Energy metabolism in Drosophila and its application to the study of obesity and diabetes

N Chatterjee, N Perrimon - Science Advances, 2021 - science.org
The organs and metabolic pathways involved in energy metabolism, and the process of ATP
production from nutrients, are comparable between humans and Drosophila melanogaster …

An overview of the insulin signaling pathway in model organisms Drosophila melanogaster and Caenorhabditis elegans

SG Biglou, WG Bendena, I Chin-Sang - Peptides, 2021 - Elsevier
The insulin/insulin-like growth factor signaling pathway is an evolutionary conserved
pathway across metazoans and is required for development, metabolism and behavior. This …

Drosophila insulin‐like peptides: from expression to functions – a review

U Semaniuk, V Piskovatska… - Entomologia …, 2021 - Wiley Online Library
Insulin‐like peptides (ILPs) belong to the insulin superfamily and act as hormones,
neuromediators, and growth factors during the post‐embryonic life‐cycle stages of insects …

Metabolic Syndrome: Lessons from Rodent and Drosophila Models

MV Vatashchuk, MM Bayliak, VV Hurza… - BioMed Research …, 2022 - Wiley Online Library
Overweight and obesity are health conditions tightly related to a number of metabolic
complications collectively called “metabolic syndrome”(MetS). Clinical diagnosis of MetS …