Biomedical implants have been widely used in various orthopedic treatments, including total
hip arthroplasty, joint arthrodesis, fracture fixation, non-union, dental repair, etc. The modern …

In biomaterials science, it is nowadays well accepted that improving the biointegration of
dental and orthopedic implants with surrounding tissues is a major goal. However, implant …

The culture of bone marrow derived mesenchymal stem cells (MSCs), as well as the control
of its differentiation toward different tissue lineage, is a very important part of tissue …

There is currently an unmet need for the supply of autologous, patient-specific stem cells for
regenerative therapies in the clinic. Mesenchymal stem cell differentiation can be driven by …

The current development of nanobiotechnologies requires a better understanding of cell–
surface interactions on the nanometre scale. Recently, advances in nanoscale patterning …

Millions of people lose or damage their organs or tissues due to disease, birth defects, or
accidents each year. Stem cells, such as embryonic stem cells (ESCs), induced pluripotent …

Two important goals in stem cell research are to control the cell proliferation without
differentiation and to direct the differentiation into a specific cell lineage when desired. Here …

We generated, on titanium surfaces, self-assembled layers of vertically oriented TiO2
nanotubes with defined diameters between 15 and 100 nm and show that adhesion …

Tissue engineering is a promising strategy to treat tissue and organ loss or damage caused
by injury or disease. During the past two decades, mesenchymal stem cells (MSCs) have …

Tendon is a specific connective tissue composed of parallel collagen fibers. The effect of this
tissue-specific matrix orientation on stem cell differentiation has not been investigated. This …