Atherosclerosis in chronic kidney disease: more, less, or just different?

JM Valdivielso, D Rodríguez-Puyol… - … , and vascular biology, 2019 - Am Heart Assoc
Patients with chronic kidney disease (CKD) are at an increased risk of premature mortality,
mainly from cardiovascular causes. The association between CKD on hemodialysis and …

Role of vitamin D beyond the skeletal function: a review of the molecular and clinical studies

M Umar, KS Sastry, AI Chouchane - International journal of molecular …, 2018 - mdpi.com
The classical function of Vitamin D, which involves mineral balance and skeletal
maintenance, has been known for many years. With the discovery of vitamin D receptors in …

The anti-inflammatory effects of short chain fatty acids on lipopolysaccharide-or tumor necrosis factor α-stimulated endothelial cells via activation of GPR41/43 and …

M Li, BCAM Van Esch, PAJ Henricks… - Frontiers in …, 2018 - frontiersin.org
Background and Aim: Previously, we found that short chain fatty acids (SCFA) inhibit LPS or
TNFα-induced endothelial inflammatory responses and excessive vascular cell adhesion …

Vitamin D and its role in the lipid metabolism and the development of atherosclerosis

AM Surdu, O Pînzariu, DM Ciobanu, AG Negru… - Biomedicines, 2021 - mdpi.com
Vitamin D, a crucial hormone in the homeostasis and metabolism of calcium bone, has lately
been found to produce effects on other physiological and pathological processes …

The multiple effects of vitamin D against chronic diseases: from reduction of lipid peroxidation to updated evidence from clinical studies

M Berretta, V Quagliariello, A Bignucolo, S Facchini… - Antioxidants, 2022 - mdpi.com
Background: Vitamin D exerts multiple beneficial effects in humans, including neuronal,
immune, and bone homeostasis and the regulation of cardiovascular functions. Recent …

Vitamin D: Not just bone metabolism but a key player in cardiovascular diseases

M Izzo, A Carrizzo, C Izzo, E Cappello, D Cecere… - Life, 2021 - mdpi.com
Vitamin D is the first item of drug expenditure for the treatment of osteoporosis. Its deficiency
is a condition that affects not only older individuals but also young people. Recently, the …

Mechanism overview and target mining of atherosclerosis: Endothelial cell injury in atherosclerosis is regulated by glycolysis

R Wang, M Wang, J Ye, G Sun… - … journal of molecular …, 2021 - spandidos-publications.com
Atherosclerosis (AS) is a chronic disease with a complex pathology that may lead to several
cardiovascular and cerebrovascular diseases; however, further research is necessary to …

Vitamin D3-VDR-PTPN6 axis mediated autophagy contributes to the inhibition of macrophage foam cell formation

S Kumar, R Nanduri, E Bhagyaraj, R Kalra, N Ahuja… - Autophagy, 2021 - Taylor & Francis
Macrophage derived foam cells in atherosclerotic plaques are the major factor responsible
for the pathogenesis of atherosclerosis (AS). During advanced AS, macrophage-specific …

Vitamin D and vitamin D receptor: new insights in the treatment of hypertension

L Lin, L Zhang, C Li, Z Gai, Y Li - Current Protein and Peptide …, 2019 - ingentaconnect.com
Vitamin D, as a natural medicine, is known to regulate calcium and phosphate homeostasis.
But abundant research has shown that vitamin D also plays a regulatory role in …

Hepatocyte vitamin D receptor regulates lipid metabolism and mediates experimental diet-induced steatosis

M Bozic, C Guzmán, M Benet, S Sánchez-Campos… - Journal of …, 2016 - Elsevier
Background & Aims The pathogenesis and progression of non-alcoholic fatty liver disease
(NAFLD) is still incompletely understood. Several nuclear receptors play a role in liver lipid …