Stimuli responsive nanosonosensitizers for sonodynamic therapy

Z Jiang, W Xiao, Q Fu - Journal of Controlled Release, 2023 - Elsevier
Sonodynamic therapy (SDT) has gained significant attention in the treatment of deep tumors
and multidrug-resistant (MDR) bacterial infections due to its high tissue penetration depth …

Antimicrobial resistance and its drivers—a review

M Irfan, A Almotiri, ZA AlZeyadi - Antibiotics, 2022 - mdpi.com
Antimicrobial resistance (AMR) is a critical issue in health care in terms of mortality, quality of
services, and financial damage. In the battle against AMR, it is crucial to recognize the …

Fast multiplex bacterial PCR of bronchoalveolar lavage for antibiotic stewardship in hospitalised patients with pneumonia at risk of Gram-negative bacterial infection …

AM Darie, N Khanna, K Jahn, M Osthoff… - The Lancet …, 2022 - thelancet.com
Background PCR-based testing has transformed the management of suspected respiratory
viral infections. We aimed to determine whether multiplex bacterial PCR of bronchoalveolar …

Phages against pathogenic bacterial biofilms and biofilm-based infections: a review

S Liu, H Lu, S Zhang, Y Shi, Q Chen - Pharmaceutics, 2022 - mdpi.com
Bacterial biofilms formed by pathogens are known to be hundreds of times more resistant to
antimicrobial agents than planktonic cells, making it extremely difficult to cure biofilm-based …

Recent advances in the detection of base modifications using the Nanopore sequencer

L Xu, M Seki - Journal of human genetics, 2020 - nature.com
DNA and RNA modifications have important functions, including the regulation of gene
expression. Existing methods based on short-read sequencing for the detection of …

Effects of heavy metals and antibiotics on antibiotic resistance genes and microbial communities in soil

Y Fu, Y Zhu, H Dong, J Li, W Zhang, Y Shao… - Process Safety and …, 2023 - Elsevier
With rapid developments in livestock and poultry farming, antibiotics and heavy metals are
entering the soil environment as feed additives. However, their relationships with antibiotic …

Molecular mechanisms of acquired antifungal drug resistance in principal fungal pathogens and EUCAST guidance for their laboratory detection and clinical …

TR Rogers, PE Verweij, M Castanheira… - Journal of …, 2022 - academic.oup.com
The increasing incidence and changing epidemiology of invasive fungal infections continue
to present many challenges to their effective management. The repertoire of antifungal drugs …

Beyond antibiotics: photo/sonodynamic approaches for bacterial theranostics

X Pang, D Li, J Zhu, J Cheng, G Liu - Nano-micro letters, 2020 - Springer
Rapid evolution and propagation of multidrug resistance among bacterial pathogens are
outpacing the development of new antibiotics, but antimicrobial photodynamic therapy …

Single-cell pathogen diagnostics for combating antibiotic resistance

H Li, K Hsieh, PK Wong, KE Mach, JC Liao… - Nature Reviews …, 2023 - nature.com
Bacterial infections and antimicrobial resistance are a major cause for morbidity and
mortality worldwide. Antimicrobial resistance often arises from antimicrobial misuse, where …

[HTML][HTML] Liquid biopsy for infectious diseases: a focus on microbial cell-free DNA sequencing

D Han, R Li, J Shi, P Tan, R Zhang, J Li - Theranostics, 2020 - ncbi.nlm.nih.gov
Metagenomic next-generation sequencing (mNGS) of microbial cell-free DNA (mcfDNA
sequencing) is becoming an attractive diagnostic modality for infectious diseases, allowing …