Phage display and other peptide display technologies

W Jaroszewicz, J Morcinek-Orłowska… - FEMS Microbiology …, 2022 - academic.oup.com
Phage display technology, which is based on the presentation of peptide sequences on the
surface of bacteriophage virions, was developed over 30 years ago. Improvements in phage …

[HTML][HTML] Advances in antibody phage display technology

L Ledsgaard, A Ljungars, C Rimbault, CV Sørensen… - Drug Discovery …, 2022 - Elsevier
Phage display technology can be used for the discovery of antibodies for research,
diagnostic, and therapeutic purposes. In this review, we present and discuss key parameters …

Phage display derived monoclonal antibodies: from bench to bedside

MA Alfaleh, HO Alsaab, AB Mahmoud… - Frontiers in …, 2020 - frontiersin.org
Monoclonal antibodies (mAbs) have become one of the most important classes of
biopharmaceutical products, and they continue to dominate the universe of …

Development of a SARS-CoV-2-specific biosensor for antigen detection using scFv-Fc fusion proteins

HY Kim, JH Lee, MJ Kim, SC Park, M Choi… - Biosensors and …, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a newly emerged human infectious
disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In a …

Current clinical landscape and global potential of bacteriophage therapy

NM Hitchcock, D Devequi Gomes Nunes, J Shiach… - Viruses, 2023 - mdpi.com
In response to the global spread of antimicrobial resistance, there is an increased demand
for novel and innovative antimicrobials. Bacteriophages have been known for their potential …

Laboratory testing methods for novel severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2)

RJ D'Cruz, AW Currier, VB Sampson - Frontiers in cell and …, 2020 - frontiersin.org
Following the first reports of coronavirus disease-19 (COVID-19) by China to the World
Health Organization (WHO) on 31st December 2019, more than 4,302,774 novel severe …

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

C Benz, M Ali, I Krystkowiak, L Simonetti… - Molecular Systems …, 2022 - embopress.org
Specific protein–protein interactions are central to all processes that underlie cell
physiology. Numerous studies have together identified hundreds of thousands of human …

An overview on display systems (phage, bacterial, and yeast display) for production of anticancer antibodies; advantages and disadvantages

SZB Mahdavi, F Oroojalian, S Eyvazi, M Hejazi… - International Journal of …, 2022 - Elsevier
Antibodies as ideal therapeutic and diagnostic molecules are among the top-selling drugs
providing considerable efficacy in disease treatment, especially in cancer therapy …

[HTML][HTML] Engineered M13 phage as a novel therapeutic bionanomaterial for clinical applications: From tissue regeneration to cancer therapy

C Chang, W Guo, X Yu, C Guo, N Zhou, X Guo… - Materials Today Bio, 2023 - Elsevier
Bacteriophages (phages) are nanostructured viruses with highly selective antibacterial
properties that have gained attention beyond eliminating bacteria. Specifically, M13 phages …

Recent progress on rapid lateral flow assay-based early diagnosis of COVID-19

Y Zhang, Y Chai, Z Hu, Z Xu, M Li, X Chen… - … in Bioengineering and …, 2022 - frontiersin.org
The outbreak of the coronavirus disease 2019 (COVID-19) has resulted in enormous losses
worldwide. Through effective control measures and vaccination, prevention and curbing …