Regulation of the hypoxia-inducible factor (HIF) by pro-inflammatory cytokines
Hypoxia and inflammation are frequently co-incidental features of the tissue
microenvironment in a wide range of inflammatory diseases. While the impact of hypoxia on …
microenvironment in a wide range of inflammatory diseases. While the impact of hypoxia on …
Inhibition of Nuclear Factor Kappa B as a Therapeutic Target for Lung Cancer.
M Li, P Liu, B Wang, J Zhou… - Alternative Therapies in …, 2022 - search.ebscohost.com
Context• A wide variety of malignancies common to humans display abnormal constitutive
expression of nuclear factor kappa beta (NF-κβ). The study of NF-κβ can increase …
expression of nuclear factor kappa beta (NF-κβ). The study of NF-κβ can increase …
Optimized 2-methoxyestradiol invasomes fortified with apamin: A promising approach for suppression of A549 lung cancer cells
ZA Awan, SA AlGhamdi, NA Alhakamy… - Drug Delivery, 2022 - Taylor & Francis
Certain anticancer agents selectively target the nucleus of cancer cells. One such drug is 2-
methoxyestradiol (2ME), which is used for treating lung cancer. To improve the therapeutic …
methoxyestradiol (2ME), which is used for treating lung cancer. To improve the therapeutic …
Expression of Serum sLOX‐1 in Patients with Non‐Small‐Cell Lung Cancer and Its Correlation with Lipid Metabolism
F Hao, J Chen, J Wu, X Ge, X Lv… - Canadian Respiratory …, 2022 - Wiley Online Library
Objective. The aim of this study was to investigate the expression level of soluble LOX‐1
(sLOX‐1) in the serum of non‐small‐cell lung cancer (NSCLC) patients and its correlation …
(sLOX‐1) in the serum of non‐small‐cell lung cancer (NSCLC) patients and its correlation …
Terpene-based novel invasomes: pioneering cancer treatment strategies in traditional medicine
Health care workers have faced a significant challenge because of the rise in cancer
incidence around the world during the past 10 years. Among various forms of malignancy …
incidence around the world during the past 10 years. Among various forms of malignancy …
The role of vasodilator-stimulated phosphoproteins in the development of malignant tumors
J Gui, H Zhou, H Wan, D Yang, Q Liu… - Current Cancer Drug …, 2024 - benthamdirect.com
Vasodilator-stimulated phosphoprotein (VASP) is an actin-binding protein that includes
three structural domains: Enabled/VASP homolog1 (EVH1), EVH2, and proline-rich (PRR) …
three structural domains: Enabled/VASP homolog1 (EVH1), EVH2, and proline-rich (PRR) …
Network pharmacology approach reveals the potential immune function activation and tumor cell apoptosis promotion of Xia Qi decoction in lung cancer
S Zhang, Y Wang - Medical Sciences, 2019 - mdpi.com
As the leading cause of cancer death worldwide, lung cancer (LC) has seriously affected
human health and longevity. Chinese medicine is a complex system guided by traditional …
human health and longevity. Chinese medicine is a complex system guided by traditional …
SBS 3.1, a novel natural product small molecule regulates TNF-α-induced NF-κB activation and key signals of inflammation to promote apoptosis in lung cancer …
A Kumar - Journal of Biomolecular Structure and Dynamics, 2024 - Taylor & Francis
Chronic inflammation leads to many maladies in lung cancer. Tumor necrosis factor-alpha (T
NF-α), a pleiotropic proinflammatory cytokine regulates the activation of the nuclear factor-κB …
NF-α), a pleiotropic proinflammatory cytokine regulates the activation of the nuclear factor-κB …
Traditional chinese medicine xihuang wan inhibited Lewis lung carcinoma in a syngeneic model, equivalent to cytotoxic chemotherapy, by altering multiple signaling …
Z Zhang, J Wang, H Duan, D Liu, X Zhou, X Lin… - in vivo, 2021 - iv.iiarjournals.org
Background/Aim: Xihuang Wan (XHW), a traditional Chinese medicine (TCM), has been
used in China for a variety of cancers including lung cancer. The present study evaluated …
used in China for a variety of cancers including lung cancer. The present study evaluated …