This review aims to assess and recommend approaches for targeted and agnostic High
Throughput Sequencing of RNA viruses in a variety of sample matrices. HTS also referred to …

The COVID-19 pandemic and heightened perception of the risk of emerging viral infections
have boosted the efforts to better understand the virome or complete repertoire of viruses in …

Though rare, breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), a
CD30+ T-cell lymphoma associated with textured breast implants, has adversely impacted …

Metagenomic sequencing is becoming widespread in biomedical and environmental
research, and the pace is increasing even more thanks to nanopore sequencing. With a …

Background In recent years, metagenomic Next-Generation Sequencing (mNGS) has
increasingly been used for an accurate assumption-free virological diagnosis. However, the …

The emergence of clinical metagenomics as an unbiased, hypothesis-free approach to
diagnostic testing is set to fundamentally alter the way infectious diseases are detected …

High‐throughput sequencing is a powerful tool, but suffers biases and errors that must be
accounted for to prevent false biological conclusions. Such errors include batch effects; …

Viral metagenomics next-generation sequencing (mNGS) is increasingly being used to
characterize the human virome. The impact of viral nucleic extraction on virome profiling has …

Recurrent urinary tract infections (UTIs) are a challenging clinical entity that can be
frustrating for patient and physician alike. Repeated rounds of antibiotics can select for …

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease with
a complex clinical presentation and an unknown etiology. Various viral infections have been …