Developing nociceptor-selective treatments for acute and chronic pain

S Jayakar, J Shim, S Jo, BP Bean, I Singeç… - Science translational …, 2021 - science.org
Despite substantial efforts dedicated to the development of new, nonaddictive analgesics,
success in treating pain has been limited. Clinically available analgesic agents generally …

Postoperative pain management in enhanced recovery pathways

CK Cheung, JO Adeola, SS Beutler… - Journal of Pain …, 2022 - Taylor & Francis
Postoperative pain is a common but often inadequately treated condition. Enhanced
recovery pathways (ERPs) are increasingly being utilized to standardize perioperative care …

[HTML][HTML] Pharmacotherapeutic pain management in patients undergoing laparoscopic cholecystectomy: A review

B Jiang, S Ye - Advances in Clinical and Experimental …, 2022 - advances.umw.edu.pl
Laparoscopic cholecystectomy is widely performed because it results in a relatively easier
pain management and shorter hospital stay. Although postoperative pain following …

NSAIDs for Pain Control During the Peri-Operative Period of Hip Fracture Surgery: A Systematic Review

W Pommier, EM Minoc, PM Morice, P Lescure… - Drugs & Aging, 2024 - Springer
Background Hip fracture (HF) mostly affects older adults and is responsible for increased
morbidity and mortality. Non-steroidal anti-inflammatory drugs (NSAIDs) are part of the peri …

Adverse effects of nonsteroidal anti-inflammatory drugs in critically ill patients: A scoping review

JR Martin, M Yu, BL Erstad - American Journal of Health-System …, 2023 - academic.oup.com
Purpose Nonsteroidal anti-inflammatory drugs (NSAIDs) are often recommended as opioid-
sparing agents. The objective of this scoping review was to conduct a thorough search of the …

Single‐dose intravenous ibuprofen for acute postoperative pain in adults

MKC Ferguson, R Schumann… - Cochrane Database …, 2021 - cochranelibrary.com
Background Postoperative administration of non‐steroidal anti‐inflammatory drugs
(NSAIDs) reduces patient opioid requirements and, in turn, may reduce the incidence and …

Postoperative administration of ketorolac compared to other drugs for pain control after third molar surgery: A meta‐analysis of double‐blind, randomized, clinical trials

MA Isiordia‐Espinoza, ÁJ Alonso‐Castro… - British Journal of …, 2022 - Wiley Online Library
Aims The aim of this study was to evaluate the analgesic effectiveness and adverse
reactions of ketorolac in comparison with other drugs when administered postoperatively …

[PDF][PDF] A review on transdermal patches used as an anti-inflammatory agent

D Choudhury, KN Dutta, R Kalita - Asian Journal of Pharmaceutical …, 2021 - academia.edu
The transdermal drug delivery system is widely accepted due to its numerous advantages as
it is a non-invasive drug administration process with prolonged therapeutic effect, reduced …

Evidence‐based safety profile of oral ketorolac in adults: Systematic review and meta‐analysis

V Esparza‐Villalpando, G Ortiz‐Barroso… - Pharmacology …, 2024 - Wiley Online Library
The primary objective of the present review was to report the safety profile of oral ketorolac
in adults using the systematic review and meta‐analysis methodology based on clinical …

Non-Opioid Analgesics and Adjuvants after Surgery in Adults with Obesity: Systematic Review with Network Meta-Analysis of Randomized Controlled Trials

M Carron, E Tamburini, F Linassi, T Pettenuzzo… - Journal of Clinical …, 2024 - mdpi.com
Background/Objectives: Managing postoperative pain in patients with obesity is challenging.
Although using a combination of pain relief methods is recommended for these patients, the …