The Candida pathogenic species complex

SA Turner, G Butler - Cold Spring Harbor …, 2014 - perspectivesinmedicine.cshlp.org
Candida species are the most common causes of fungal infection. Approximately 90% of
infections are caused by five species: Candida albicans, Candida glabrata, Candida …

Biofilms and vulvovaginal candidiasis

C Rodríguez-Cerdeira, MC Gregorio… - Colloids and Surfaces B …, 2019 - Elsevier
Candida species, including C. albicans, are part of the mucosal flora of most healthy women,
and inhabit the gastrointestinal and genitourinary tracts. Under favourable conditions, they …

Pilon: an integrated tool for comprehensive microbial variant detection and genome assembly improvement

BJ Walker, T Abeel, T Shea, M Priest, A Abouelliel… - PloS one, 2014 - journals.plos.org
Advances in modern sequencing technologies allow us to generate sufficient data to
analyze hundreds of bacterial genomes from a single machine in a single day. This potential …

The Candida Genome Database (CGD): incorporation of Assembly 22, systematic identifiers and visualization of high throughput sequencing data

MS Skrzypek, J Binkley, G Binkley… - Nucleic acids …, 2016 - academic.oup.com
Abstract The Candida Genome Database (CGD, http://www. candidagenome. org/) is a
freely available online resource that provides gene, protein and sequence information for …

Genetic and phenotypic intra-species variation in Candida albicans

MP Hirakawa, DA Martinez, S Sakthikumar… - Genome …, 2015 - genome.cshlp.org
Candida albicans is a commensal fungus of the human gastrointestinal tract and a prevalent
opportunistic pathogen. To examine diversity within this species, extensive genomic and …

Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum

A Miles, Z Iqbal, P Vauterin, R Pearson… - Genome …, 2016 - genome.cshlp.org
The malaria parasite Plasmodium falciparum has a great capacity for evolutionary
adaptation to evade host immunity and develop drug resistance. Current understanding of …

The type VI secretion system deploys antifungal effectors against microbial competitors

K Trunk, J Peltier, YC Liu, BD Dill, L Walker… - Nature …, 2018 - nature.com
Interactions between bacterial and fungal cells shape many polymicrobial communities.
Bacteria elaborate diverse strategies to interact and compete with other organisms …

Gene flow contributes to diversification of the major fungal pathogen Candida albicans

J Ropars, C Maufrais, D Diogo… - Nature …, 2018 - nature.com
Elucidating population structure and levels of genetic diversity and recombination is
necessary to understand the evolution and adaptation of species. Candida albicans is the …

Gene Essentiality Analyzed by In Vivo Transposon Mutagenesis and Machine Learning in a Stable Haploid Isolate of Candida albicans

ES Segal, V Gritsenko, A Levitan, B Yadav, N Dror… - MBio, 2018 - Am Soc Microbiol
Knowing the full set of essential genes for a given organism provides important information
about ways to promote, and to limit, its growth and survival. For many non-model organisms …

[HTML][HTML] Molecular epidemiology, phylogeny and evolution of Candida albicans

BA McManus, DC Coleman - Infection, Genetics and Evolution, 2014 - Elsevier
A small number of Candida species form part of the normal microbial flora of mucosal
surfaces in humans and may give rise to opportunistic infections when host defences are …