[HTML][HTML] Activity, structural features and in silico digestion of antidiabetic peptides

C Berraquero-García, F Rivero-Pino, JL Ospina… - Food Bioscience, 2023 - Elsevier
Food antidiabetic peptides inhibit the enzymes involved in the regulation of the glycemic
index (eg α-amylase, α-glucosidase and dipeptidyl peptidase-IV (DPP-IV)). This work …

Rp3: Ribosome profiling-assisted proteogenomics improves coverage and confidence during microprotein discovery

E Vieira de Souza, A L. Bookout, CA Barnes… - Nature …, 2024 - nature.com
There has been a dramatic increase in the identification of non-canonical translation and a
significant expansion of the protein-coding genome. Among the strategies used to identify …

[HTML][HTML] A Novel Workflow for In Silico Prediction of Bioactive Peptides: An Exploration of Solanum lycopersicum By-Products

F Morena, C Cencini, E Calzoni, S Martino, C Emiliani - Biomolecules, 2024 - mdpi.com
Resource-intensive processes currently hamper the discovery of bioactive peptides (BAPs)
from food by-products. To streamline this process, in silico approaches present a promising …

Multi-protease approach for the improved identification and molecular characterization of small proteins and short open reading frame-encoded peptides

PT Kaulich, L Cassidy, J Bartel… - Journal of Proteome …, 2021 - ACS Publications
The identification of proteins below approximately 70–100 amino acids in bottom-up
proteomics is still a challenging task due to the limited number of peptides generated by …

Proteome-pI 2.0: proteome isoelectric point database update

LP Kozlowski - Nucleic acids research, 2022 - academic.oup.com
Abstract Proteome-pI 2.0 is an update of an online database containing predicted isoelectric
points and p K a dissociation constants of proteins and peptides. The isoelectric point—the …

[HTML][HTML] Potential of umami molecules against SARS-CoV-2 (Omicron) S-RBD/hACE2 interaction: an in-silico study

Z Cui, S Wang, Y Xu, Y Liu, W Wang - Journal of Future Foods, 2025 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enter human cells by
binding its spike protein receptor-binding domain (S-RBD) with human angiotensin …

[HTML][HTML] Bioactive properties of peptide fractions from Brazilian soy protein hydrolysates: In silico evaluation and experimental evidence

TC Farias, JP Abreu, JPS Oliveira, AF Macedo… - Food Hydrocolloids for …, 2023 - Elsevier
Soybeans are a known source of dietary proteins and potential bioactive peptides. In this
study, a protein hydrolysate from soybean protein concentrate was produced using papain …

[HTML][HTML] Antioxidant Peptides from Sacha Inchi Meal: An In Vitro, Ex Vivo, and In Silico Approach

E Torres-Sánchez, I Lorca-Alonso… - Foods, 2024 - mdpi.com
Plant-derived antioxidant peptides safeguard food against oxidation, helping to preserve its
flavor and nutrients, and hold significant potential for use in functional food development …

Neutrophil-mediated type IV collagen degradation is elevated in patients with mild endoscopic ulcerative colitis reflecting early mucosal destruction

MS Alexdottir, M Pehrsson, V Domislovic… - Scientific Reports, 2024 - nature.com
Neutrophils play a significant role in sustaining chronic inflammation in Inflammatory Bowel
Disease. The intestinal basement membrane acts as a barrier for immunological …

A genome-scale atlas reveals complex interplay of transcription and translation in an archaeon

APR Lorenzetti, U Kusebauch, LS Zaramela, WJ Wu… - Msystems, 2023 - Am Soc Microbiol
The scale of post-transcriptional regulation and the implications of its interplay with other
forms of regulation in environmental acclimation are underexplored for organisms of the …