Stimuli-responsive natural gums-based drug delivery systems for cancer treatment

K Soleimani, H Derakhshankhah, M Jaymand… - Carbohydrate …, 2021 - Elsevier
Chemotherapy as the main cancer treatment method has non-specific effects and various
side-effects. Accordingly, significant attempts have been conducted to enhance its efficacy …

Chitosan-Based Hydrogel for the Dual Delivery of Antimicrobial Agents Against Bacterial Methicillin-Resistant Staphylococcus aureus Biofilm-Infected Wounds

VO Fasiku, CA Omolo, N Devnarain, UH Ibrahim… - ACS …, 2021 - ACS Publications
Chronic wound infections caused by antibiotic-resistant bacteria have become a global
health concern. This is attributed to the biofilm-forming ability of bacteria on wound surfaces …

Synthesis of gum acacia-silver nanoparticles based hydrogel composites and their comparative anti-bacterial activity

K Virk, K Sharma, S Kapil, V Kumar, V Sharma… - Journal of Polymer …, 2022 - Springer
An interpenetrating polymer network (IPN) containing gum acacia (GA), poly (methacrylic
acid)(MAA), and poly (acrylic acid)(AA) was developed using a two-step aqueous …

A hyaluronic acid-based nanogel for the co-delivery of nitric oxide (NO) and a novel antimicrobial peptide (AMP) against bacterial biofilms

VO Fasiku, CA Omolo, LW Kiruri, N Devnarain… - International Journal of …, 2022 - Elsevier
Biofilms are a global health concern because they are associated with chronic and recurrent
infections as well as resistance to conventional antibiotics. The aim of this study was to …

Electrosprayed alginate nanoparticles as CRISPR plasmid DNA delivery carrier: preparation, optimization, and characterization

B Alallam, S Altahhan, M Taher, MH Mohd Nasir… - Pharmaceuticals, 2020 - mdpi.com
Therapeutic gene editing is becoming more feasible with the emergence of the Clustered
Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein …

Optimization of carboxymethyl cellulose-gum Arab-based hydrogel beads for anticancer drugs delivery

AA Ghawanmeh, LL Tan, GAM Ali, MA Assiri… - Journal of Molecular …, 2024 - Elsevier
Response surface methodology was successfully utilized to optimize the amounts of
carboxymethyl cellulose (CMC) and gum Arab (GA) to fabricate hydrogel beads for the …

Sustained release properties of liquid crystal functionalized poly (amino acid) s nanoparticles

Z Hu, G Wang, S Zhao, S Jiang, J Hu… - Journal of Molecular …, 2023 - Elsevier
Drug-loaded nanoparticles can lower the adverse effects of antitumor drugs and have good
biosafety. Herein, a series of amphiphilic poly (amino acid) s materials were designed to …

Construction of nano-drug delivery and antitumor system of stimuli-responsive polypeptides

Z Hu, R Zhang, S Xu, J Wang, X Li, J Hu… - Colloids and Surfaces B …, 2023 - Elsevier
The size of the nanoparticles is moderate and the dispersion is well, which will not be
recognized nonspecifically and clearance by the endothelial reticular system. In this study …

Arabic Gum Grafted PEGDMA Hydrogels: Synthesis, Physico-Chemical Characterization and In-vitro Release of Hydrophobic Drug

SM Ibrahim, TY Yin, M Misran - Macromolecular Research, 2020 - Springer
Hydrogel development using natural and synthetic polymers for biomedical applications
have shown promising properties for drug delivery due to virtuous stimuli response and …

Novel pH-responsive polyvinyl alcohol/Arabic gum/magnesium oxide nanobiocomposite for oral colon targeted drug delivery

A Moghadam, S Kariminia, MS Mobarakeh - Journal of Drug Delivery …, 2022 - Elsevier
In this study, we used a novel pH-responsive polyvinyl alcohol/Arabic gum/magnesium
oxide (PVA/AG/MgO nanobiocomposite) as an oral colon targeted delivery system for …