Oxygen (O 2) toxicity remains a concern, particularly to the lung. This is mainly related to
excessive production of reactive oxygen species (ROS). Supplemental O 2, ie inspiratory O …

The understanding of acute respiratory distress syndrome (ARDS) has evolved greatly since
it was first described in a 1967 case series, with several subsequent updates to the definition …

OBJECTIVES: This review aims to: 1) identify the key circuit and patient factors affecting
systemic oxygenation, 2) summarize the literature reporting the association between …

Cardiac surgery is a distinctive surgical discipline that often necessitates the use of
cardiopulmonary bypass (CPB) and full anticoagulation intraoperatively, along with varying …

Over the past decade, the interest in oxygen toxicity has led to various observational studies
and randomized clinical trials in critically ill patients, assessing the association with …

Purpose Patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO)
frequently develop arterial hyperoxaemia, which may be harmful. However, lower oxygen …

Background Within-breath oscillations in arterial oxygen tension (PaO2) can be detected
using fast responding intra-arterial oxygen sensors in animal models. These PaO2 signals …

Introduction Acute respiratory distress syndrome (ARDS) still represents a major challenge
with high mortality rates and altered quality of life. Many well-designed studies have failed to …

Determining oxygenation targets in acute respiratory distress syndrome (ARDS) remains a
challenge. Although oxygenation targets have been used since ARDS was first described …

Background Prone position ventilation (PPV) has been recommended for patients with acute
respiratory distress syndrome (ARDS) to improve oxygenation. However, whether prolonged …