Chemistry and biology of ferritin

M Plays, S Müller, R Rodriguez - Metallomics, 2021 - academic.oup.com
Iron is an essential element required by cells and has been described as a key player in
ferroptosis. Ferritin operates as a fundamental iron storage protein in cells forming …

Unity in the biochemistry of the iron-storage proteins ferritin and bacterioferritin

K Honarmand Ebrahimi, PL Hagedoorn… - Chemical …, 2015 - ACS Publications
Life on earth is dependent on the catalytic activity of a number of different metal ions in their
polypeptide scaffold. Of these metals iron is widely used for catalysis of many reactions by …

Ferritin: a promising nanoreactor and nanocarrier for bionanotechnology

A Mohanty, A Parida, RK Raut… - ACS bio & med chem …, 2022 - ACS Publications
The essence of bionanotechnology lies in the application of nanotechnology/nanomaterials
to solve the biological problems. Quantum dots and nanoparticles hold potential biomedical …

Optical Monitoring of In Situ Iron Loading into Single, Native Ferritin Proteins

A Yousefi, C Ying, CDJ Parmenter, M Assadipapari… - Nano Letters, 2023 - ACS Publications
Ferritin is a protein that stores and releases iron to prevent diseases associated with iron
dysregulation in plants, animals, and bacteria. The conversion between iron-loaded holo …

Bacterial iron detoxification at the molecular level

JM Bradley, DA Svistunenko, MT Wilson… - Journal of Biological …, 2020 - ASBMB
Iron is an essential micronutrient, and, in the case of bacteria, its availability is commonly a
growth-limiting factor. However, correct functioning of cells requires that the labile pool of …

Iron, ferritin, hereditary ferritinopathy, and neurodegeneration

BB Muhoberac, R Vidal - Frontiers in neuroscience, 2019 - frontiersin.org
Cellular growth, function, and protection require proper iron management, and ferritin plays
a crucial role as the major iron sequestration and storage protein. Ferritin is a 24 subunit …

Ferritin nanocages: a versatile platform for nanozyme design

C Wang, Q Liu, X Huang, J Zhuang - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Nanozymes are a class of nanomaterials with enzyme-like activities and have attracted
increasing attention due to their potential applications in biomedicine. However, nanozyme …

Ferritins: furnishing proteins with iron

JM Bradley, NE Le Brun, GR Moore - JBIC Journal of Biological Inorganic …, 2016 - Springer
Ferritins are a superfamily of iron oxidation, storage and mineralization proteins found
throughout the animal, plant, and microbial kingdoms. The majority of ferritins consist of 24 …

Observation of gold sub-nanocluster nucleation within a crystalline protein cage

B Maity, S Abe, T Ueno - Nature communications, 2017 - nature.com
Protein scaffolds provide unique metal coordination environments that promote
biomineralization processes. It is expected that protein scaffolds can be developed to …

Kinetics of ferritin self-assembly by laser light scattering: Impact of subunit concentration, pH, and ionic strength

A Mohanty, MK, SS Jena, RK Behera - Biomacromolecules, 2021 - ACS Publications
Ferritins, the cellular iron repositories, are self-assembled, hollow spherical nanocage
proteins composed of 24 subunits. The self-assembly process in ferritin generates the …