Opioids form an important component of general anesthesia and perioperative analgesia.
Discharge opioid prescriptions are identified as a contributor for persistent opioid use and …

Automation empowers self-sustainable adaptive processes and personalized services in
many industries. The implementation of the integrated healthcare paradigm built on Health …

Study objective Opioid-free anaesthesia may enhance postoperative recovery by reducing
opioid-related side effects such as nausea, hyperalgesia or tolerance. The objective was to …

Background The majority of postoperative patients report moderate to severe pain, possibly
related to opioid underdosing or overdosing during surgery. Objective guidance of opioid …

We present a narrative review focusing on the new role of nociception monitor in
intraoperative anesthetic management. Higher invasiveness of surgery elicits a higher …

The feasibility of OFA is evident. However, there are limitations of this approach that warrant
discussion including the potential for adverse drug interactions with multimodal analgesics …

Maintaining optimum analgesia in anesthetized patients is challenging due to the inability to
self-report pain or exhibit pain-related behaviours. The Analgesia Nociception Index …

Most patients report pain during their stay in the intensive care unit (ICU). Pain is
multifactorial and can be caused by critical illness, invasive treatment, and standard care …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder, which affects 1 in 44
children and may cause severe disabilities. Besides socio-communicational difficulties and …

Background Reducing intra-operative opioid consumption benefits patients by decreasing
postoperative opioid-related adverse events. We assessed whether opioid-free anesthesia …