[HTML][HTML] The conserved substrate binding site of mitochondrial carriers

ERS Kunji, AJ Robinson - Biochimica et Biophysica Acta (BBA) …, 2006 - Elsevier
Mitochondrial carriers transport nucleotides, co-factors and metabolic intermediates across
the inner mitochondrial membrane permeability barrier. They belong to a family of …

The mitochondrial citrate carrier: metabolic role and regulation of its activity and expression

GV Gnoni, P Priore, MJH Geelen, L Siculella - IUBMB life, 2009 - Wiley Online Library
The citrate carrier (CiC), a nuclear‐encoded protein located in the mitochondrial inner
membrane, is a member of the mitochondrial carrier family. CiC plays an important role in …

Mitochondrial carriers in the cytoplasmic state have a common substrate binding site

AJ Robinson, ERS Kunji - Proceedings of the National …, 2006 - National Acad Sciences
Mitochondrial carriers link biochemical pathways in the cytosol and mitochondrial matrix by
transporting substrates across the inner mitochondrial membrane. Substrate recognition is …

Structure of the lethal phage pinhole

T Pang, CG Savva, KG Fleming… - Proceedings of the …, 2009 - National Acad Sciences
Perhaps the simplest of biological timing systems, bacteriophage holins accumulate during
the phage morphogenesis period and then trigger to permeabilize the cytoplasmic …

SCAM analysis of Panx1 suggests a peculiar pore structure

J Wang, G Dahl - Journal of General Physiology, 2010 - rupress.org
Vertebrates express two families of gap junction proteins: the well-characterized connexins
and the pannexins. In contrast to connexins, pannexins do not appear to form gap junction …

BRCA1 and its network of interacting partners

CM Christou, K Kyriacou - Biology, 2012 - mdpi.com
BRCA1 is a large multi-domain protein with a pivotal role in maintaining genome stability
and cell cycle progression. Germline mutations in the BRCA1 gene confer an estimated …

[HTML][HTML] Insights into the malfunctioning of the mitochondrial citrate carrier: Implications for cell pathology

V Zara, G Assalve, A Ferramosca - … Acta (BBA)-Molecular Basis of Disease, 2023 - Elsevier
The mitochondrial citrate carrier (CIC) is a member of the mitochondrial carrier family and is
responsible for the transit of tricarboxylates and dicarboxylates across the inner membrane …

The mitochondrial oxoglutarate carrier: from identification to mechanism

M Monné, DV Miniero, F Bisaccia… - Journal of bioenergetics …, 2013 - Springer
Abstract The 2-oxoglutarate carrier (OGC) belongs to the mitochondrial carrier protein family
whose members are responsible for the exchange of metabolites, cofactors and nucleotides …

Functional and structural role of amino acid residues in the even-numbered transmembrane α-helices of the bovine mitochondrial oxoglutarate carrier

AR Cappello, R Curcio, DV Miniero, I Stipani… - Journal of molecular …, 2006 - Elsevier
The mitochondrial oxoglutarate carrier exchanges cytosolic malate for 2-oxoglutarate from
the mitochondrial matrix. Orthologs of the carrier have a high degree of amino acid …

Identification of the pore-lining residues of the BM2 ion channel protein of influenza B virus

C Ma, CS Soto, Y Ohigashi, A Taylor, V Bournas… - Journal of Biological …, 2008 - ASBMB
The influenza B virus BM2 proton-selective ion channel is essential for virus uncoating, a
process that occurs in the acidic environment of the endosome. The BM2 channel causes …