Antimicrobial peptides: an update on classifications and databases

A Bin Hafeez, X Jiang, PJ Bergen, Y Zhu - International journal of …, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …

Antiviral peptides as promising therapeutic drugs

LCP Vilas Boas, ML Campos, RLA Berlanda… - Cellular and Molecular …, 2019 - Springer
While scientific advances have led to large-scale production and widespread distribution of
vaccines and antiviral drugs, viruses still remain a major cause of human diseases today …

CAMPR4: a database of natural and synthetic antimicrobial peptides

U Gawde, S Chakraborty, FH Waghu… - Nucleic Acids …, 2023 - academic.oup.com
There has been an exponential increase in the design of synthetic antimicrobial peptides
(AMPs) for its use as novel antibiotics. Synthetic AMPs are substantially enriched in residues …

Machine learning prediction of antimicrobial peptides

G Wang, II Vaisman, ML van Hoek - Computational peptide science …, 2022 - Springer
Antibiotic resistance constitutes a global threat and could lead to a future pandemic. One
strategy is to develop a new generation of antimicrobials. Naturally occurring antimicrobial …

Antimicrobial peptides: an alternative for innovative medicines?

JP Da Costa, M Cova, R Ferreira, R Vitorino - Applied microbiology and …, 2015 - Springer
Antimicrobial peptides are small molecules with activity against bacteria, yeasts, fungi,
viruses, bacteria, and even tumor cells that make these molecules attractive as therapeutic …

CAMP: Collection of sequences and structures of antimicrobial peptides

FH Waghu, L Gopi, RS Barai, P Ramteke… - Nucleic acids …, 2014 - academic.oup.com
Antimicrobial peptides (AMPs) are gaining importance as anti-infective agents. Here we
describe the updated Collection of Antimicrobial Peptide (CAMP) database, available online …

Designing improved active peptides for therapeutic approaches against infectious diseases

B Gomes, MT Augusto, MR Felício, A Hollmann… - Biotechnology …, 2018 - Elsevier
Infectious diseases are one of the main causes of human morbidity and mortality. In the last
few decades, pathogenic microorganisms' resistance to conventional drugs has been …

DRAMP: a comprehensive data repository of antimicrobial peptides

L Fan, J Sun, M Zhou, J Zhou, X Lao, H Zheng, H Xu - Scientific reports, 2016 - nature.com
The growing problem of antibiotic-resistant microorganisms results in an urgent need for
substitutes to conventional antibiotics with novel modes of action and effective activities …

A large‐scale structural classification of antimicrobial peptides

HT Lee, CC Lee, JR Yang, JZC Lai… - BioMed research …, 2015 - Wiley Online Library
Antimicrobial peptides (AMPs) are potent drug candidates against microbial organisms such
as bacteria, fungi, parasites, and viruses. AMPs have abundant sequences and structures …

AVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses

A Qureshi, N Thakur, H Tandon… - Nucleic acids …, 2014 - academic.oup.com
Antiviral peptides (AVPs) have exhibited huge potential in inhibiting viruses by targeting
various stages of their life cycle. Therefore, we have developed AVPdb, available online at …