Cyclic oxonium derivatives of cobalt and iron bis (dicarbollides) and their use in organic synthesis

AA Druzina, AV Shmalko, IB Sivaev… - Russian Chemical …, 2021 - iopscience.iop.org
The rapid progress in the chemistry of carboranes and other polyhedral boron compounds
makes the development of methods for the synthesis of their various functional derivatives a …

Cobalt bis (dicarbollide) anion and its derivatives

BP Dash, R Satapathy, BR Swain, CS Mahanta… - Journal of …, 2017 - Elsevier
Owing to high chemical and thermal stability, ionic character, low nucleophilicity and
peculiar solubility, cobalt bis (dicarbollide) anion occupies a unique position among the …

Synthesis of conjugates of polyhedral boron hydrides with nucleosides

AA Druzina, VI Bregadze, AF Mironov… - Russian Chemical …, 2016 - iopscience.iop.org
Methods of synthesis of the conjugates of polyhedral boron hydrides with natural and non-
natural nucleosides are overviewed. These conjugates are of interest for their potential …

Metallacarborane sulfamides: Unconventional, specific, and highly selective inhibitors of carbonic anhydrase IX

B Grüner, J Brynda, V Das, V Šícha… - Journal of Medicinal …, 2019 - ACS Publications
Carbonic anhydrase IX (CAIX) is a transmembrane enzyme that regulates pH in hypoxic
tumors and promotes tumor cell survival. Its expression is associated with the occurrence of …

Synthesis and Antibacterial Activity Studies of the Conjugates of Curcumin with closo-Dodecaborate and Cobalt Bis(Dicarbollide) Boron Clusters

AA Druzina, NE Grammatikova, OB Zhidkova… - Molecules, 2022 - mdpi.com
A series of novel conjugates of cobalt bis (dicarbollide) and closo-dodecaborate with
curcumin were synthesized by copper (I)-catalyzed azide-alkyne cycloaddition. These …

Cobalt bis (dicarbollide) alkylsulfonamides: Potent and highly selective inhibitors of tumor specific carbonic anhydrase IX

B Grüner, M Kugler, S El Anwar, J Holub… - …, 2021 - Wiley Online Library
Carbonic anhydrase IX (CAIX) is an enzyme expressed on the surface of cells in hypoxic
tumors. It plays a role in regulation of tumor pH and promotes thus tumor cell survival and …

Synthesis and evaluation of thymidine kinase 1-targeting carboranyl pyrimidine nucleoside analogs for boron neutron capture therapy of cancer

HK Agarwal, A Khalil, K Ishita, W Yang… - European journal of …, 2015 - Elsevier
A library of sixteen 2nd generation amino-and amido-substituted carboranyl pyrimidine
nucleoside analogs, designed as substrates and inhibitors of thymidine kinase 1 (TK1) for …

Synthesis and in vitro antiviral activity of lipophilic pyrimidine nucleoside/carborane conjugates

M Białek-Pietras, AB Olejniczak, E Paradowska… - Journal of …, 2015 - Elsevier
A series of novel conjugates of para-carborane with 5-ethynyl-uridine or 2′-deoxyuridine
were synthesized. The conjugates were prepared by Sonogashira coupling of para …

[HTML][HTML] Do the same chlorinated organophosphorus flame retardants that cause cytotoxicity and DNA damage share the same pathway?

S Yuan, H Zhang, S Wang, X Jiang, M Ma, Y Xu… - Ecotoxicology and …, 2024 - Elsevier
Organophosphorus flame retardants (OPFRs) have been frequently detected with relatively
high concentrations in various environmental media and are considered emerging …

Charge‐compensated metallacarborane building blocks for conjugation with peptides

R Frank, VM Ahrens, S Boehnke… - …, 2016 - Wiley Online Library
The cobalt bis (dicarbollide) complex [commo‐3, 3′‐Co (1, 2‐C2B9H11) 2]− has captured
much attention in biochemical and medical contexts, in particular for the treatment of tumors …