Single-cell transcriptomics: A new tool for studying diabetic kidney disease

ZH Mao, ZX Gao, Y Liu, DW Liu, ZS Liu… - Frontiers in Physiology, 2023 - frontiersin.org
The kidney is a complex organ comprising various functional partitions and special cell
types that play important roles in maintaining homeostasis in the body. Diabetic kidney …

[HTML][HTML] Ferroptosis in Health and Disease

C Berndt, H Alborzinia, VS Amen, S Ayton, U Barayeu… - Redox Biology, 2024 - Elsevier
Ferroptosis is a pervasive non-apoptotic form of cell death highly relevant in various
degenerative diseases and malignancies. The hallmark of ferroptosis is uncontrolled and …

Update on selected high-grade renal cell carcinomas of the kidney: FH-deficient, ALK-rearranged, and medullary carcinomas

YB Chen - Advances in Anatomic Pathology, 2024 - journals.lww.com
High-grade renal cell carcinoma (RCC), often diagnosed at advanced stages, significantly
contributes to renal cancer-related mortality. This review explores the progress in …

CA-125 as a Biomarker in Renal Medullary Carcinoma: Integrated Molecular Profiling, Functional Characterization, and Prospective Clinical Validation

SL Grimm, M Karki, KA Blum, JP Bertocchio… - Clinical Cancer …, 2025 - aacrjournals.org
Purpose: Renal medullary carcinoma (RMC) is a highly aggressive malignancy defined by
the loss of the SMARCB1 tumor suppressor. It mainly affects young individuals of African …

[PDF][PDF] Epidemiology, pathology, and pathogenesis of renal cell carcinoma

MB Atkins, TK Choueiri - UpToDate Retrieved June, 2016 - simplevas.net
Renal cell carcinomas (RCCs), which originate within the renal cortex, are responsible for
80 to 85 percent of all primary renal neoplasms. Transitional cell carcinomas of the renal …

Advances in integrating single-cell sequencing data to unravel the mechanism of ferroptosis in cancer

Z Du, Y Shi, J Tan - Briefings in Functional Genomics, 2024 - academic.oup.com
Ferroptosis, a commonly observed type of programmed cell death caused by abnormal
metabolic and biochemical mechanisms, is frequently triggered by cellular stress. The …

[HTML][HTML] Cellular landscape of adrenocortical carcinoma at single-nuclei resolution

DS Tourigny, B Altieri, KA Secener, S Sbiera… - Molecular and Cellular …, 2024 - Elsevier
Adrenocortical carcinoma (ACC) is a rare yet devastating tumour of the adrenal gland with a
molecular pathology that remains incompletely understood. To gain novel insights into the …

[HTML][HTML] Ferroptosis as an emerging target in sickle cell disease

V Fortuna, J Lima, GF Oliveira, YS Oliveira… - Current Research in …, 2024 - Elsevier
Sickle cell disease (SCD) is an inherited hemoglobin disorder marked by red blood cell
sickling, resulting in severe anemia, painful episodes, extensive organ damage, and …

Renal Medullary Carcinoma: The Zebra Amongst the Horses

D Dalela, S Batie, A Carolan, B Schlomer, R Collins… - Urology, 2024 - Elsevier
A 13-year old Latino male presented with recurrent gross hematuria, 5 cm right-sided poorly
defined heterogeneous mass, enlarged retrocaval lymph nodes, and 1.2 cm paratracheal …