Rett Syndrome (RTT) is a severe, rare, and progressive developmental disorder with
patients displaying neurological regression and autism spectrum features. The affected …

Methylation, a key epigenetic modification, is essential for regulating gene expression and
protein function without altering the DNA sequence, contributing to various biological …

Rett syndrome (RTT) and CDKL5 deficiency disorder (CDD) are two rare X-linked
developmental brain disorders with overlapping but distinct phenotypic features. This review …

Rett syndrome is an X‐linked neurodevelopmental disorder caused by mutation of Mecp2
gene and primarily affects females. Glial cell dysfunction has been implicated in in Rett …

Highlights•MeCP2 regulates the timing of critical periods in sensory cortex.•MeCP2 binds
and drives expression of genes implicated in synaptic plasticity and the expression of …

Rett syndrome (RTT) is a rare, X-linked neurodevelopmental disorder typically affecting
females, resulting in a range of symptoms including autistic features, intellectual impairment …

Rett syndrome (RTT) is a severe neurodevelopmental disorder that is associated in most
cases with mutations in the transcriptional regulator MECP2. At present, there are no …

Background: Elevated glutamate production and release from glial cells is a common feature
of many CNS disorders. Inhibitors of glutaminase (GLS), the enzyme responsible for …

Brain function is critically dependent on correct circuit assembly. Microglia are well‐known
for their important roles in immunological defense and neural plasticity, but whether they can …

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition that is
characterized by differences in social interaction, repetitive behaviors, restricted interests …