Transitional cell (urothelial) carcinoma of the bladder is the second most common urologic
malignancy and is one of the best understood neoplasms, with relatively well-defined …

It has been estimated that chronic infections with viruses, bacteria and parasites contribute
to 17· 8% of the global burden of cancer, although only a relatively small proportion of the …

Abstract Background: Bladder cancer (BCa) remains a lethal malignancy that can be cured if
detected early. DNA hypermethylation is a common epigenetic abnormality in cancer that …

With an estimated 74,000 new cases and 16,000 deaths for 2015, BC is the fifth most
frequent malignancy in the United States. 1 Urothelial carcinoma of the bladder (UCB) …

Telomerase is a reverse transcriptase capable of utilizing an integrated RNA component as
a template to add protective tandem telomeric single strand DNA repeats, TTAGGG, to the …

Telomerase activity has been measured in a wide variety of cancerous and non-cancerous
tissue types, and the vast majority of clinical studies have shown a direct correlation …

This review focuses on the promising potential of nucleic acids in body fluids such as blood
and urine as diagnostic, prognostic, predictive and monitoring biomarkers in urologic …

Abstract The International Agency for Research on Cancer (IARC) identifies ten infectious
agents (viruses, bacteria, parasites) able to induce cancer disease in humans. Among …

It is now widely believed that there are two major pathways for urothelial carcinogenesis.
One pathway usually involves mutation of FGF receptor 3 and gives rise to low-grade …

Introduction• Methods for telomere length and telomerase detection• Telomere length as a
potential diagnostic marker in cancer‐Breast cancer‐Prostate cancer‐Other cancer types• …