Surfactant protein D in respiratory and non-respiratory diseases

GL Sorensen - Frontiers in medicine, 2018 - frontiersin.org
Surfactant protein D (SP-D) is a multimeric collectin that is involved in innate immune
defense and expressed in pulmonary, as well as non-pulmonary, epithelia. SP-D exerts …

The international workshop on meibomian gland dysfunction: report of the subcommittee on tear film lipids and lipid–protein interactions in health and disease

KB Green-Church, I Butovich, M Willcox… - … & visual science, 2011 - iovs.arvojournals.org
Understanding the molecular composition (eg, proteins and lipids) of the tear film (TF) and
the contribution of the meibomian gland to the TF is critical in gaining knowledge about TF …

Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus

CR Baskin, H Bielefeldt-Ohmann… - Proceedings of the …, 2009 - National Acad Sciences
The mechanisms responsible for the virulence of the highly pathogenic avian influenza
(HPAI) and of the 1918 pandemic influenza virus in humans remain poorly understood. To …

A machine-generated view of the role of blood glucose levels in the severity of COVID-19

E Logette, C Lorin, C Favreau, E Oshurko… - Frontiers in Public …, 2021 - frontiersin.org
SARS-CoV-2 started spreading toward the end of 2019 causing COVID-19, a disease that
reached pandemic proportions among the human population within months. The reasons for …

The impact of vitamin D on fetal and neonatal lung maturation. A systematic review

S Lykkedegn, GL Sorensen… - … of Physiology-Lung …, 2015 - journals.physiology.org
Respiratory distress syndrome (RDS) and bronchopulmonary dysplasia (BPD) are major
complications to preterm birth. Hypovitaminosis D is prevalent in pregnancy. We …

[HTML][HTML] Biomarkers for the acute respiratory distress syndrome: how to make the diagnosis more precise

MI García-Laorden, JA Lorente, C Flores… - Annals of …, 2017 - ncbi.nlm.nih.gov
The acute respiratory distress syndrome (ARDS) is an acute inflammatory process of the
lung caused by a direct or indirect insult to the alveolar-capillary membrane. Currently …

The effects of fluticasone with or without salmeterol on systemic biomarkers of inflammation in chronic obstructive pulmonary disease

DD Sin, SFP Man, DD Marciniuk, G Ford… - American journal of …, 2008 - atsjournals.org
Rationale: Small studies have suggested that inhaled corticosteroids can suppress systemic
inflammation in chronic obstructive pulmonary disease (COPD). Objectives: To determine …

Protein kinase C and toll‐like receptor signaling

DJ Loegering, MR Lennartz - Enzyme research, 2011 - Wiley Online Library
Protein kinase C (PKC) is a family of kinases that are implicated in a plethora of diseases,
including cancer and cardiovascular disease. PKC isoforms can have different, and …

SP-D attenuates LPS-induced formation of human neutrophil extracellular traps (NETs), protecting pulmonary surfactant inactivation by NETs

R Arroyo, MA Khan, M Echaide, J Pérez-Gil… - Communications …, 2019 - nature.com
An exacerbated amount of neutrophil extracellular traps (NETs) can cause dysfunction of
systems during inflammation. However, host proteins and factors that suppress NET …

Targeted PPARγ deficiency in alveolar macrophages disrupts surfactant catabolism

AD Baker, A Malur, BP Barna, S Ghosh… - Journal of lipid …, 2010 - ASBMB
Surfactant accumulates in alveolar macrophages of granulocyte-macrophage colony-
stimulating factor (GM-CSF) knockout (KO) mice and pulmonary alveolar proteinosis (PAP) …