In the management of neurological diseases, the identification and quantification of axonal
damage could allow for the improvement of diagnostic accuracy and prognostic assessment …

Alzheimer's disease (AD) is a progressive neurodegenerative disease with a complex and
heterogeneous pathophysiology. The number of people living with AD is predicted to …

Introduction A systematic review and meta-analysis was performed regarding the diagnostic
performance of neurofilament light chain (NfL) in CSF and blood. Methods A database …

Alzheimer's disease is a progressive, clinically heterogeneous, and particularly complex
neurodegenerative disease characterized by a decline in cognition. Over the last two …

Alzheimer's disease (AD) is increasingly prevalent worldwide, and disease‐modifying
treatments may soon be at hand; hence, now, more than ever, there is a need to develop …

The Precision Neurology development process implements systems theory with system
biology and neurophysiology in a parallel, bidirectional research path: a combined …

Introduction We investigated relations between amyloid-β (Aβ) status, apolipoprotein E
(APOE) ε4, and cognition, with cerebrospinal fluid markers of neurogranin (Ng) …

Neurofilament proteins have been validated as specific body fluid biomarkers of neuro-
axonal injury. The advent of highly sensitive analytical platforms that enable reliable …

Neurofilament light (NFL) is a putative biomarker of neurodegeneration. This study
evaluates the correlative association of NFL with Alzheimer's disease (AD) indices. Relevant …

The search for diagnostic and prognostic biomarkers for neurodegenerative conditions is of
high importance, since these disorders may present difficulties in differential diagnosis …