Phase I and pharmacokinetic study of irofulven administered weekly or biweekly in advanced solid tumor patients
J Alexandre, E Raymond, MO Kaci, EC Brain… - Clinical cancer …, 2004 - AACR
Abstract Purpose: We performed a Phase I and pharmacokinetic study to determine the
maximum tolerated dose of irofulven (6-hydroxymethylacylfulvene; MGI-114, MGI PHARMA …
maximum tolerated dose of irofulven (6-hydroxymethylacylfulvene; MGI-114, MGI PHARMA …
A phase I and pharmacokinetic study of irofulven and cisplatin administered in a 30-min infusion every two weeks to patients with advanced solid tumors
W Hilgers, S Faivre, S Chieze, J Alexandre… - Investigational new …, 2006 - Springer
Background: To determine maximum tolerated dose (MTD), recommended dose, safety and
pharmacokinetics of irofulven combined with cisplatin in advanced solid tumor patients …
pharmacokinetics of irofulven combined with cisplatin in advanced solid tumor patients …