Skeletal muscle hypertrophy and regeneration: interplay between the myogenic regulatory factors (MRFs) and insulin-like growth factors (IGFs) pathways

N Zanou, P Gailly - Cellular and Molecular Life Sciences, 2013 - Springer
Adult skeletal muscle can regenerate in response to muscle damage. This ability is
conferred by the presence of myogenic stem cells called satellite cells. In response to stimuli …

Skeletal muscle regeneration in cardiotoxin-induced muscle injury models

Y Wang, J Lu, Y Liu - International journal of molecular sciences, 2022 - mdpi.com
Skeletal muscle injuries occur frequently in daily life and exercise. Understanding the
mechanisms of regeneration is critical for accelerating the repair and regeneration of …

Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling

A Britschgi, A Bill, H Brinkhaus… - Proceedings of the …, 2013 - National Acad Sciences
The calcium-activated chloride channel anoctamin 1 (ANO1) is located within the 11q13
amplicon, one of the most frequently amplified chromosomal regions in human cancer, but …

Roles of mTOR signaling in tissue regeneration

X Wei, L Luo, J Chen - Cells, 2019 - mdpi.com
The mammalian target of rapamycin (mTOR), is a serine/threonine protein kinase and
belongs to the phosphatidylinositol 3-kinase (PI3K)-related kinase (PIKK) family. mTOR …

Hydrogels preserve native phenotypes of valvular fibroblasts through an elasticity-regulated PI3K/AKT pathway

H Wang, MW Tibbitt, SJ Langer… - Proceedings of the …, 2013 - National Acad Sciences
Matrix elasticity regulates proliferation, apoptosis, and differentiation of many cell types
across various tissues. In particular, stiffened matrix in fibrotic lesions has been shown to …

Red (635 nm), near-infrared (808 nm) and violet-blue (405 nm) photobiomodulation potentiality on human osteoblasts and mesenchymal stromal cells: a …

A Tani, F Chellini, M Giannelli, D Nosi… - International journal of …, 2018 - mdpi.com
Photobiomodulation (PBM) has been used for bone regenerative purposes in different fields
of medicine and dentistry, but contradictory results demand a skeptical look for its potential …

Role of TRPC channels in store-operated calcium entry

HL Ong, LB de Souza, IS Ambudkar - … entry pathways in non-excitable cells, 2016 - Springer
Store-operated calcium entry (SOCE) is a ubiquitous Ca 2+ entry pathway that is activated in
response to depletion of Ca 2+ stores within the endoplasmic reticulum (ER) and contributes …

ATP-induced increase in intracellular calcium levels and subsequent activation of mTOR as regulators of skeletal muscle hypertrophy

N Ito, UT Ruegg, S Takeda - International journal of molecular sciences, 2018 - mdpi.com
Intracellular signaling pathways, including the mammalian target of rapamycin (mTOR) and
the mitogen-activated protein kinase (MAPK) pathway, are activated by exercise, and …

Classical transient receptor potential 1 (TRPC1): channel or channel regulator?

A Dietrich, M Fahlbusch, T Gudermann - Cells, 2014 - mdpi.com
In contrast to other Classical Transient Receptor Potential TRPC channels the function of
TRPC1 as an ion channel is a matter of debate, because it is often difficult to obtain …

[HTML][HTML] Ambient and supplemental magnetic fields promote myogenesis via a TRPC1-mitochondrial axis: evidence of a magnetic mitohormetic mechanism

JLY Yap, YK Tai, J Fröhlich, CHH Fong, JN Yin… - The FASEB …, 2019 - ncbi.nlm.nih.gov
We show that both supplemental and ambient magnetic fields modulate myogenesis. A lone
10 min exposure of myoblasts to 1.5 mT amplitude supplemental pulsed magnetic fields …