Bioengineering strategies for restoring vision

J Cehajic-Kapetanovic, MS Singh, E Zrenner… - Nature biomedical …, 2023 - nature.com
Late-stage retinal degenerative disease involving photoreceptor loss can be treated by
optogenetic therapy, cell transplantation and retinal prostheses. These approaches aim to …

A new frontier: The convergence of nanotechnology, brain machine interfaces, and artificial intelligence

GA Silva - Frontiers in neuroscience, 2018 - frontiersin.org
A confluence of technological capabilities is creating an opportunity for machine learning
and artificial intelligence (AI) to enable “smart” nanoengineered brain machine interfaces …

Potential therapeutic strategies for photoreceptor degeneration: the path to restore vision

F Karamali, S Behtaj, S Babaei-Abraki… - Journal of translational …, 2022 - Springer
Photoreceptors (PRs), as the most abundant and light-sensing cells of the neuroretina, are
responsible for converting light into electrical signals that can be interpreted by the brain. PR …

Implantation of electronic visual prosthesis for blindness restoration

J Jang, H Kim, YM Song, JU Park - Optical materials express, 2019 - opg.optica.org
Loss of sight significantly degrades the quality of human life. Various methods for restoring
the vision of blind patients have been studied and range from biological ways to electronic …

Visual prosthesis: interfacing stimulating electrodes with retinal neurons to restore vision

A Barriga-Rivera, L Bareket, J Goding… - Frontiers in …, 2017 - frontiersin.org
The bypassing of degenerated photoreceptors using retinal neurostimulators is helping the
blind to recover functional vision. Researchers are investigating new ways to improve visual …

Highly flexible single-unit resolution all printed neural interface on a bioresorbable backbone

RM Almasri, W AlChamaa… - ACS Applied Bio …, 2020 - ACS Publications
Neural interfaces are the parts of the neural prosthesis that are in contact with the target
tissue. The mechanical, chemical, and electrical properties of these interfaces can be a …

Optimizing the fabrication of a 3D high-resolution implant for neural stimulation

G Shpun, N Farah, Y Chemla, A Markus… - Journal of Biological …, 2023 - Springer
Background Tissue-integrated micro-electronic devices for neural stimulation hold great
potential in restoring the functionality of degenerated organs, specifically, retinal prostheses …

[HTML][HTML] Toward the next generation of retinal neuroprosthesis: Visual computation with spikes

Z Yu, JK Liu, S Jia, Y Zhang, Y Zheng, Y Tian, T Huang - Engineering, 2020 - Elsevier
A neuroprosthesis is a type of precision medical device that is intended to manipulate the
neuronal signals of the brain in a closed-loop fashion, while simultaneously receiving stimuli …

Vertically aligned nanostructured topographies for human neural stem cell differentiation and neuronal cell interrogation

E Lestrell, CM O'Brien, R Elnathan… - Advanced …, 2021 - Wiley Online Library
Neurodegenerative disorders are a widespread global health concern caused by aging,
disease, and trauma, for which there are limited treatment options. Stem cell therapies …

Nanoinformatics and nanomodeling: Recent developments in computational nanodrug design and delivery systems

S Ahmad, FN Khan, A Ramlal, S Begum, S Qazi… - … for medical applications, 2023 - Elsevier
After computational drug designing and genome analysis developments, nanoinformatics is
emerging as a next-generation drug designing and simulation study for the nanodrug …