Metals associated neurodegeneration in Parkinson's disease: Insight to physiological, pathological mechanisms and management

K Raj, P Kaur, GD Gupta, S Singh - Neuroscience Letters, 2021 - Elsevier
Parkinson's disease (PD) is a deliberately progressive neurological disorder, arises due to
degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc). The …

Deep brain stimulation mechanisms: beyond the concept of local functional inhibition

JM Deniau, B Degos, C Bosch… - European Journal of …, 2010 - Wiley Online Library
Deep brain electrical stimulation has become a recognized therapy in the treatment of a
variety of motor disorders and has potentially promising applications in a wide range of …

Response inhibition subprocesses and dopaminergic pathways: basal ganglia disease effects

C Beste, R Willemssen, C Saft, M Falkenstein - Neuropsychologia, 2010 - Elsevier
Response inhibition is a component of executive functions, which can be divided into distinct
subprocesses by means of event-related potentials (ERPs). These subprocesses are (pre) …

Selective activation of neuronal targets with sinusoidal electric stimulation

DK Freeman, DK Eddington… - Journal of …, 2010 - journals.physiology.org
Electric stimulation of the CNS is being evaluated as a treatment modality for a variety of
neurological, psychiatric, and sensory disorders. Despite considerable success in some …

Mechanisms of deep brain stimulation in movement disorders as revealed by changes in stimulus frequency

MJ Birdno, WM Grill - Neurotherapeutics, 2008 - Springer
Deep brain stimulation (DBS) is an established treatment for symptoms in movement
disorders and is under investigation for symptom management in persons with psychiatric …

[图书][B] Cortical oscillations in health and disease

R Traub, M Whittington - 2010 - books.google.com
This book first reviews the case that brain oscillations not only are important for cognition, as
long suspected, but also play a part in the expression of signs and symptoms of …

The neural correlates of upper limb motor blocks in Parkinson's disease and their relation to freezing of gait

S Vercruysse, J Spildooren, E Heremans… - Cerebral …, 2014 - academic.oup.com
Due to basal ganglia dysfunction, bimanual motor performance in Parkinson patients
reportedly relies on compensatory brain activation in premotor–parietal–cerebellar …

Convergent evidence for abnormal striatal synaptic plasticity in dystonia

DA Peterson, TJ Sejnowski, H Poizner - Neurobiology of disease, 2010 - Elsevier
Dystonia is a functionally disabling movement disorder characterized by abnormal
movements and postures. Although substantial recent progress has been made in …

Translating neurobehavioural endpoints of developmental neurotoxicity tests into in vitro assays and readouts

C van Thriel, RHS Westerink, C Beste, AS Bale… - Neurotoxicology, 2012 - Elsevier
The developing nervous system is particularly vulnerable to chemical insults. Exposure to
chemicals can result in neurobehavioural alterations, and these have been used as …

Intermittent neural synchronization in Parkinson's disease

LL Rubchinsky, C Park, RM Worth - Nonlinear dynamics, 2012 - Springer
Motor symptoms of Parkinson's disease are related to the excessive synchronized oscillatory
activity in the beta frequency band (around 20 Hz) in the basal ganglia and other parts of the …