The endothelium, a cellular monolayer lining the blood vessel wall, plays a critical role in
maintaining multiorgan health and homeostasis. Endothelial functions in health include …

Atherosclerosis, the chronic accumulation of cholesterol-rich plaque within arteries, is
associated with a broad spectrum of cardiovascular diseases including myocardial …

Abstract An Expert Panel convened by the National Lipid Association previously developed
a consensus set of recommendations for the patient-centered management of dyslipidemia …

Background Secondary progressive multiple sclerosis, for which no satisfactory treatment
presently exists, accounts for most of the disability in patients with multiple sclerosis …

BACKGROUND In the acute respiratory distress syndrome (ARDS), inflammation in the
lungs and other organs can cause life-threatening organ failure. Inhibitors of 3-hydroxy-3 …

The shuttling of leukocytes between the bloodstream and interstitial tissues involves different
locomotion strategies that are governed by locally presented soluble and cell-bound signals …

Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …

Abstract Purpose of Review Chronic inflammation has been recognized as one of the most
important pathophysiological mechanisms' initiation and progression of atherosclerosis …

Background Cardiovascular disease (CVD) is more frequent among people with HIV (PWH)
and may relate to traditional and nontraditional factors, including inflammation and immune …

Statins, which are widely used to treat hypercholesterolemia, have anti-inflammatory and
anti-oxidant effects. These are thought to be responsible for the potential effects of statins on …