Epilepsy often develops in patients with glioma, and the two conditions share common
pathogenic mechanisms. Altered expression of glutamate transporters, including the cystine …

Common pathophysiological mechanisms have emerged for different neurological and
neuropsychiatric conditions. In particular, mechanisms of oxidative stress, immuno …

Epilepsy is one of the most common serious brain disorders, affecting about 1% of the
population all over the world. Ginkgo biloba extract (GbE) and L-carnitine (LC) reportedly …

Epilepsy is a challenging brain disorder that is often difficult to treat with conventional
therapies. The gut microbiota has been shown to play an important role in the development …

The present study was designed to examine the possible neuroprotective and antiepileptic
effects of metformin (Metf) in a rat model of pentylenetetrazole (PTZ)-induced epilepsy and …

Peroxisome proliferator-activated receptor (PPAR)-γ is involved in both normal physiological
processes and pathology of various diseases. The purpose of this study was to explore the …

Alcoholic liver disease (ALD) is one of the predominant causes of liver-related morbidity and
mortality worldwide. However, effective therapy for ALD is still lacking. Wogonin, a major …

Borneol, a bicyclic monoterpene, can easily cross the blood brain barrier and was found to
possess gamma amino butyric acid (GABA) modulatory effect. The present study was aimed …

In mammals, peroxisome proliferators activated receptors (PPARs), the nuclear hormone
receptors, have been reported to be involved in seizure control. Selective agonists and …

Three members of the peroxisome proliferator-activated receptor (PPAR) family, PPARα,
PPARγ, and PPARβ/δ, have been investigated widely over the past few decades. Although …