The growing increase in antibiotic-resistant bacteria has led to the search for new
antibacterial agents capable of overcoming the resistance problem. In recent years …

Smart biomaterials can sense and react to physiological or external environmental stimuli
(eg, mechanical, chemical, electrical, or magnetic signals). The last decades have seen …

Microenvironment-responsive hydrogels present high potential in treating refractory wounds
due to their capability of on-demand drug release. In this study, a specially designed …

The increasing morbidity of oral diseases, such as dental caries, periodontitis and oral
cancer, has greatly compromised the life quality of humans. With the rapid development of …

Dental caries is one of the most common bacteria-related oral diseases, and the cariogenic
bacteria play critical roles in its pathogenesis. Antibacterial therapy is regarded as an …

Despite its reputation as the most widely used restorative dental material currently, resin-
based materials have acknowledged shortcomings. As most systematic survival studies of …

Present worldwide difficulties in healthcare and the environment have motivated the
investigation and research of novel materials in an effort to find novel techniques to address …

This review addresses the rationale of recurrent and/or residual caries associated with resin
composite restorations alongside current strategies and evidence-based recommendations …

Nanoparticles based on metal and metallic oxide have become a novel trend for dental use
as they interfere with bacterial metabolism and prevent biofilm formation. Metal and metal …

Secondary caries is one of the leading causes of resin-based dental restoration failure. It is
initiated at the interface of an existing restoration and the restored tooth surface. It is mainly …