Candida parapsilosis: from genes to the bedside

R Tóth, J Nosek, HM Mora-Montes… - Clinical microbiology …, 2019 - Am Soc Microbiol
Patients with suppressed immunity are at the highest risk for hospital-acquired infections.
Among these, invasive candidiasis is the most prevalent systemic fungal nosocomial …

The fungal CYP51s: their functions, structures, related drug resistance, and inhibitors

J Zhang, L Li, Q Lv, L Yan, Y Wang… - Frontiers in microbiology, 2019 - frontiersin.org
CYP51 (Erg11) belongs to the cytochrome P450 monooxygenase (CYP) superfamily and
mediates a crucial step of the synthesis of ergosterol, which is a fungal-specific sterol. It is …

The Candida pathogenic species complex

SA Turner, G Butler - Cold Spring Harbor …, 2014 - perspectivesinmedicine.cshlp.org
Candida species are the most common causes of fungal infection. Approximately 90% of
infections are caused by five species: Candida albicans, Candida glabrata, Candida …

A comprehensive comparison of RNA-Seq-based transcriptome analysis from reads to differential gene expression and cross-comparison with microarrays: a case …

I Nookaew, M Papini, N Pornputtapong… - Nucleic acids …, 2012 - academic.oup.com
RNA-seq, has recently become an attractive method of choice in the studies of
transcriptomes, promising several advantages compared with microarrays. In this study, we …

Recent advances in understanding the human fungal pathogen hypoxia response in disease progression

C Puerner, S Vellanki, JL Strauch… - Annual Review of …, 2023 - annualreviews.org
Fungal-mediated disease progression and antifungal drug efficacy are significantly
impacted by the dynamic infection microenvironment. At the site of infection, oxygen often …

Candida parapsilosis is a significant neonatal pathogen: a systematic review and meta-analysis

M Pammi, L Holland, G Butler, A Gacser… - The Pediatric …, 2013 - journals.lww.com
Background: Candida is the third most common cause of late-onset neonatal sepsis in
infants born at< 1500 g. Candida parapsilosis infections are increasingly reported in preterm …

CodingQuarry: highly accurate hidden Markov model gene prediction in fungal genomes using RNA-seq transcripts

AC Testa, JK Hane, SR Ellwood, RP Oliver - BMC genomics, 2015 - Springer
Background The impact of gene annotation quality on functional and comparative genomics
makes gene prediction an important process, particularly in non-model species, including …

Comparative Phenotypic Analysis of the Major Fungal Pathogens Candida parapsilosis and Candida albicans

LM Holland, MS Schröder, SA Turner, H Taff… - PLoS …, 2014 - journals.plos.org
Candida parapsilosis and Candida albicans are human fungal pathogens that belong to the
CTG clade in the Saccharomycotina. In contrast to C. albicans, relatively little is known about …

Comparative Genome Analysis and Gene Finding in Candida Species Using CGOB

SL Maguire, SS OhÉigeartaigh, KP Byrne… - Molecular biology …, 2013 - academic.oup.com
Abstract The Candida Gene Order Browser (CGOB) was developed as a tool to visualize
and analyze synteny relationships in multiple Candida species, and to provide an accurate …

Defining the transcriptomic landscape of Candida glabrata by RNA-Seq

J Linde, S Duggan, M Weber, F Horn… - Nucleic acids …, 2015 - academic.oup.com
Candida glabrata is the second most common pathogenic Candida species and has
emerged as a leading cause of nosocomial fungal infections. Its reduced susceptibility to …