Biology of lung macrophages in health and disease
H Aegerter, BN Lambrecht, CV Jakubzick - Immunity, 2022 - cell.com
Tissue-resident alveolar and interstitial macrophages and recruited macrophages are critical
players in innate immunity and maintenance of lung homeostasis. Until recently, assessing …
players in innate immunity and maintenance of lung homeostasis. Until recently, assessing …
[HTML][HTML] Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatment
Y Huang, X Guo, Y Wu, X Chen, L Feng, N Xie… - … and Targeted Therapy, 2024 - nature.com
Inflammation-associated diseases encompass a range of infectious diseases and non-
infectious inflammatory diseases, which continuously pose one of the most serious threats to …
infectious inflammatory diseases, which continuously pose one of the most serious threats to …
[HTML][HTML] Alternatively activated macrophages; a double-edged sword in allergic asthma
Background Macrophages are heterogenous phagocytic cells with an important role in the
innate immunity. They are, also, significant contributors in the adaptive immune system …
innate immunity. They are, also, significant contributors in the adaptive immune system …
[HTML][HTML] Alveolar macrophages in the resolution of inflammation, tissue repair, and tolerance to infection
Pathogen persistence in the respiratory tract is an important preoccupation, and of particular
relevance to infectious diseases such as tuberculosis. The equilibrium between elimination …
relevance to infectious diseases such as tuberculosis. The equilibrium between elimination …
Macrophage polarization and allergic asthma
Allergic asthma is associated with airway inflammation and airway hyperresponsiveness.
Macrophage polarization has been shown to have a profound impact on asthma …
Macrophage polarization has been shown to have a profound impact on asthma …
[HTML][HTML] IL33: roles in allergic inflammation and therapeutic perspectives
Interleukin (IL)-33 belongs to IL-1 cytokine family which is constitutively produced from the
structural and lining cells including fibroblasts, endothelial cells, and epithelial cells of skin …
structural and lining cells including fibroblasts, endothelial cells, and epithelial cells of skin …
[HTML][HTML] Recruited monocytes and type 2 immunity promote lung regeneration following pneumonectomy
To investigate the role of immune cells in lung regeneration, we used a unilateral
pneumonectomy model that promotes the formation of new alveoli in the remaining lobes …
pneumonectomy model that promotes the formation of new alveoli in the remaining lobes …
[HTML][HTML] FABP5 controls macrophage alternative activation and allergic asthma by selectively programming long-chain unsaturated fatty acid metabolism
Y Hou, D Wei, Z Zhang, H Guo, S Li, J Zhang, P Zhang… - Cell Reports, 2022 - cell.com
Fatty acids (FAs) are widely involved in diverse biological functions. In mice with myeloid-
specific deletion of fatty acid-binding protein 5 (FABP5), OVA-induced allergic airway …
specific deletion of fatty acid-binding protein 5 (FABP5), OVA-induced allergic airway …
[HTML][HTML] The role of type 2 innate lymphoid cells in allergic diseases
H Zheng, Y Zhang, J Pan, N Liu, Y Qin, L Qiu… - Frontiers in …, 2021 - frontiersin.org
Allergic diseases are significant diseases that affect many patients worldwide. In the past
few decades, the incidence of allergic diseases has increased significantly due to …
few decades, the incidence of allergic diseases has increased significantly due to …
Alternative macrophage activation is increased in asthma
PO Girodet, D Nguyen, JD Mancini… - American journal of …, 2016 - atsjournals.org
The immune responses of type 2 T helper cells (Th2) play an important role in asthma and
promote the differentiation of alternatively activated (M2) macrophages. M2 macrophages …
promote the differentiation of alternatively activated (M2) macrophages. M2 macrophages …