Purpose: Lymphedema of the arm is one of the most common and underestimated side
effects of breast cancer treatment. It is known to negatively affect the quality of life (QoL) in …

Urinary bladder cancer (UBC) is a common disease worldwide. At any point in time 2.7
million people have a history of UBC. The incidence of UBC varies over the world with …

Background Lynch syndrome is caused by germline mutations in MSH2, MLH1, MSH6, and
PMS2 mismatch-repair genes and leads to a high risk of colorectal and endometrial cancer …

Background Colorectal, endometrial and upper urinary tract tumours are characteristic for
Lynch syndrome (hereditary non-polyposis colon carcinoma, HNPCC). The aim of the …

Accurate estimations of lifetime risks of breast and ovarian cancer are crucial for counselling
women from BRCA1/2 families. We therefore determined breast and ovarian cancer …

Abstract Ataxia‐telangiectasia (A‐T) is an autosomal recessive neurodegenerative disorder
with multisystem involvement and cancer predisposition, caused by mutations in the A‐T …

STUDY QUESTION How do couples with a BRCA1/2 mutation decide on preimplantation
genetic diagnosis (PGD) and prenatal diagnosis (PND) for hereditary breast and ovarian …

Background Current frequent follow-up after treatment for breast cancer does not meet its
intended aims, but does depend on expensive and scarce specialized knowledge for routine …

Background: Lifetime risks are often used in communications on cancer to the general
public. The most-cited estimate for breast cancer risk (1 in 8 women), however, appears to …

The aim of this instrumental study was to compare the psychometric properties between
World Health Organization Quality of Life instrument, short form (WHOQOL-BREF), data …