Clathrin-mediated endocytosis is a key process in vesicular trafficking that transports a wide
range of cargo molecules from the cell surface to the interior. Clathrin-mediated endocytosis …

Biological membranes are complex and dynamic assemblies of lipids and proteins.
Poikilothermic organisms including bacteria, fungi, reptiles, and fish do not control their body …

Plasma membrane rupture (PMR) is the final cataclysmic event in lytic cell death. PMR
releases intracellular molecules known as damage-associated molecular patterns (DAMPs) …

G protein–coupled receptors are the largest and pharmacologically most important receptor
family and are involved in the regulation of most cell functions. Most of them reside …

Intracellular α-synuclein deposits, known as Lewy bodies, have been linked to a range of
neurodegenerative disorders, including Parkinson's disease. α-Synuclein binds to synthetic …

G-protein-coupled receptors (GPCRs) mediate many critical physiological processes. Their
spatial organization in plasma membrane (PM) domains is believed to encode signaling …

Cells are constantly submitted to external mechanical stresses, which they must withstand
and respond to. By forming a physical boundary between cells and their environment that is …

T cells are critically important for host defense against infections. T cell activation is specific
because signal initiation requires T cell receptor (TCR) recognition of foreign antigen …

Transmembrane nanostructures like ion channels and transporters perform key biological
functions by controlling flow of molecules across lipid bilayers. Much work has gone into …

Septins are conserved guanine nucleotide-binding proteins that polymerize into filaments at
the cell cortex or in association with other cytoskeletal proteins, such as actin or …